Reactome | TRIM9 [cytosol]

TRIM9 [cytosol]

Stable Identifier

R-HSA-976054

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase TRIM9, TRIM9_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9C026 TRIM9

Gene Names

TRIM9, KIAA0282, RNF91

Chain

chain:1-710

Reference Genes

BioGPS Gene:114088 TRIM9

COSMIC (genes):TRIM9 TRIM9

CTD Gene:114088 TRIM9

dbSNP Gene:114088 TRIM9

ENSEMBL:ENSG00000100505 TRIM9

HGNC:16288 TRIM9

KEGG:hsa:114088 TRIM9

Monarch:114088 TRIM9

NCBI Gene:114088 TRIM9

OMIM:606555 TRIM9

UCSC:Q9C026 TRIM9

Reference Transcript

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

madd-2 [cytosol] (Caenorhabditis elegans)

trim9 [cytosol] (Xenopus tropicalis)

TRIM9 [cytosol] (Bos taurus)

TRIM9 [cytosol] (Canis familiaris)

TRIM9 [cytosol] (Drosophila melanogaster)

TRIM9 [cytosol] (Gallus gallus)

TRIM9 [cytosol] (Mus musculus)

TRIM9 [cytosol] (Rattus norvegicus)

TRIM9 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENST00000298355, ENSP00000298355, ENST00000338969, ENSG00000100505, ENSP00000353561, ENST00000360392, ENSP00000342970

OpenTargets

ENSG00000100505

IntEnz

2.3.2.27

GeneCards

TRIM9

HPA

ENSG00000100505-TRIM9

PRO

Q9C026

Pharos - Targets

Q9C026

PDB

2DB8, 7B2S

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y297 BTRC	2	BTRC [cytosol] (R-HSA-174237) BTRC [nucleoplasm] (R-HSA-3361753)	0.831	8
UniProt:Q2TBE0 CWF19L2	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.718	6
UniProt:P50552 VASP	1	VASP [cytosol] (R-HSA-446323)	0.666	4
UniProt:P48730 CSNK1D	3	CSNK1D [cytosol] (R-HSA-380315) CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5685717) CSNK1D [nucleoplasm] (R-HSA-421305)	0.556	3
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.556	3
UniProt:Q9NV70 EXOC1	2	EXOC1 [plasma membrane] (R-HSA-2872284) EXOC1 [cytosol] (R-HSA-5623375)	0.553	2

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