Reactome | TRIM9 [cytosol]

TRIM9 [cytosol]

Stable Identifier

R-HSA-976054

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase TRIM9, TRIM9_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9C026 TRIM9

Gene Names

TRIM9, KIAA0282, RNF91

Chain

chain:1-710

Reference Genes

BioGPS Gene:114088 TRIM9

COSMIC (genes):TRIM9 TRIM9

CTD Gene:114088 TRIM9

dbSNP Gene:114088 TRIM9

ENSEMBL:ENSG00000100505 TRIM9

HGNC:16288 TRIM9

KEGG Gene (Homo sapiens):114088 TRIM9

Monarch:114088 TRIM9

NCBI Gene:114088 TRIM9

OMIM:606555 TRIM9

UCSC:Q9C026 TRIM9

Reference Transcript

Other Identifiers

0002360035

0003190164

0006350551

0102640139

114088

11720617_at

11720618_s_at

11725606_at

16792894

209859_at

230280_at

3564255

3564256

3564258

3564259

3564260

3564261

3564262

3564270

3564272

3564281

3564282

3564283

3564284

3564285

3564286

3564287

3564288

3564289

3564290

3564291

3564292

3564297

3564298

3564302

3564303

3564328

3564329

3564330

3564331

3564332

3564333

3564334

3564335

3564336

3564337

3564338

3564339

3564340

3564341

3564342

36903_at

56614_at

7979108

A_23_P205632

A_23_P205637

A_24_P321709

A_24_P369656

A_33_P3383836

D87458_at

GE57410

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005856

GO:0006464

GO:0008021

GO:0008150

GO:0008270

GO:0009056

GO:0016567

GO:0016740

GO:0019904

GO:0030054

GO:0030425

GO:0031410

GO:0042803

GO:0042995

GO:0043161

GO:0043167

GO:0043226

GO:0045202

GO:0046872

GO:0061630

HMNXSV003015808

HMNXSV003032240

HMNXSV003042122

Hs.23833.0.A1_3p_at

ILMN_1719254

ILMN_1763433

ILMN_1786697

PH_hs_0004274

TC14001127.hg

g12407402_3p_at

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

madd-2 [cytosol] (Caenorhabditis elegans)

trim9 [cytosol] (Danio rerio)

Trim9 [cytosol] (Drosophila melanogaster)

Trim9 [cytosol] (Mus musculus)

Trim9 [cytosol] (Rattus norvegicus)

TRIM9 [cytosol] (Canis familiaris)

TRIM9 [cytosol] (Gallus gallus)

TRIM9 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_443210.1, NP_055978.4, XP_011534691.1, XP_016876434.1

OpenTargets

ENSG00000100505

IntEnz

2.3.2.27

HPA

ENSG00000100505-TRIM9

GeneCards

Q9C026

Ensembl

ENST00000360392, ENSP00000298355, ENST00000298355, ENST00000338969, ENSG00000100505, ENSP00000353561, ENSP00000342970

PRO

Q9C026

Pharos - Targets

Q9C026

PDB

7B2S, 2DB8

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y297 BTRC	2	BTRC [nucleoplasm] (R-HSA-3361753) BTRC [cytosol] (R-HSA-174237)	0.781	7
UniProt:P50552 VASP	2	VASP [cytosol] (R-HSA-426404) VASP [cytosol] (R-HSA-446323)	0.666	4
UniProt:P48730 CSNK1D	3	CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5685717) CSNK1D [nucleoplasm] (R-HSA-421305) CSNK1D [cytosol] (R-HSA-380315)	0.556	3
UniProt:P05067 APP	20	APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:Q9NV70 EXOC1	2	EXOC1 [cytosol] (R-HSA-5623375) EXOC1 [plasma membrane] (R-HSA-2872284)	0.553	2