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UBE3B [cytosol]
Stable Identifier
R-HSA-976043
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin-protein ligase E3B, UBE3B_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
UBE3B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z3V4 UBE3B
Gene Names
UBE3B
Chain
chain:1-1068
Reference Genes
BioGPS Gene:89910 UBE3B
COSMIC (genes):UBE3B UBE3B
CTD Gene:89910 UBE3B
dbSNP Gene:89910 UBE3B
ENSEMBL:ENSG00000151148 UBE3B
ENSEMBL:ENSG00000151148.14 UBE3B
HGNC:13478 UBE3B
KEGG Gene (Homo sapiens):89910 UBE3B
Monarch:89910 UBE3B
NCBI Gene:89910 UBE3B
OMIM:608047 UBE3B
UCSC:Q7Z3V4 UBE3B
Reference Transcript
RefSeq:XM_017020196.1 UBE3B
RefSeq:XM_011538959.2 UBE3B
RefSeq:XM_005253987.2 UBE3B
RefSeq:NM_183415.2 UBE3B
RefSeq:NM_001270449.1 UBE3B
RefSeq:NM_130466.3 UBE3B
RefSeq:NM_001270451.1 UBE3B
RefSeq:NM_001270450.1 UBE3B
Other Identifiers
11721697_a_at
11721698_a_at
11729303_a_at
11729304_a_at
11750467_a_at
11756263_s_at
16756757
212403_PM_at
212403_at
212404_PM_s_at
212404_s_at
213822_PM_s_at
213822_s_at
3431144
3431145
3431146
3431149
3431150
3431151
3431152
3431153
3431154
3431157
3431160
3431161
3431162
3431163
3431164
3431165
3431170
3431171
3431172
3431173
3431174
3431175
3431177
3431178
3431180
3431181
3431183
3431184
3431186
3431188
3431190
3431191
3431194
3431196
3431197
3431200
3431206
3431207
3431208
40622_r_at
40623_at
7958532
89910
A_14_P113036
A_23_P99186
A_33_P3258008
A_33_P3258013
GE56380
GO:0000209
GO:0003824
GO:0004842
GO:0005515
GO:0006511
GO:0016567
GO:0016740
GO:0016874
GO:0030163
GO:0036211
GO:0061630
GO:0140096
HMNXSV003013873
HMNXSV003020763
HMNXSV003056937
Hs.17639.0.S1_3p_a_at
Hs.17639.0.S1_3p_s_at
Hs.17639.1.A1_3p_a_at
Hs.17639.1.A2_3p_at
ILMN_1752027
PH_hs_0029693
TC12000848.hg
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
HUL5 [cytosol]
(Saccharomyces cerevisiae)
NM_140022.1 [cytosol]
(Drosophila melanogaster)
ube3b [cytosol]
(Xenopus tropicalis)
oxi-1 [cytosol]
(Caenorhabditis elegans)
UBE3B [cytosol]
(Bos taurus)
UBE3B [cytosol]
(Canis familiaris)
UBE3B [cytosol]
(Danio rerio)
UBE3B [cytosol]
(Gallus gallus)
UBE3B [cytosol]
(Plasmodium falciparum)
UBE3B [cytosol]
(Schizosaccharomyces pombe)
UBE3B [cytosol]
(Sus scrofa)
Ube3b [cytosol]
(Mus musculus)
Ube3b [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_001257380.1
,
XP_005254044.1
,
NP_001257379.1
,
XP_011537261.1
,
NP_569733.2
,
NP_001257378.1
,
XP_016875685.1
,
NP_904324.1
OpenTargets
ENSG00000151148
GeneCards
Q7Z3V4
HPA
ENSG00000151148-UBE3B
Ensembl
ENST00000434735
,
ENST00000340074
,
ENST00000342494
,
ENST00000449510
,
ENSP00000440585
,
ENST00000540230
,
ENSP00000395802
,
ENSP00000342614
,
ENSP00000391529
,
ENSG00000151148
,
ENSP00000443565
,
ENST00000536398
,
ENSP00000340596
PRO
Q7Z3V4
Pharos - Targets
Q7Z3V4
Orphanet
22014
HMDB Protein
HMDBP09323
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