Reactome | IFI30 [lysosomal lumen]

IFI30 [lysosomal lumen]

Stable Identifier

R-HSA-1031704

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal lumen

Synonyms

GILT, Gamma-interferon-inducible lysosomal thiol reductase, GILT_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P13284 IFI30

Gene Names

IFI30, GILT, IP30

Chain

signal peptide:1-26, propeptide:27-57, chain:58-232, propeptide:233-250

Reference Genes

BioGPS Gene:10437 IFI30

COSMIC (genes):IFI30 IFI30

CTD Gene:10437 IFI30

dbSNP Gene:10437 IFI30

ENSEMBL:ENSG00000216490 IFI30

HGNC:5398 IFI30

KEGG:hsa:10437 IFI30

Monarch:10437 IFI30

NCBI Gene:10437 IFI30

OMIM:604664 IFI30

UCSC:P13284 IFI30

Reference Transcript

RefSeq:NM_006332.4 IFI30

Other Identifiers

10437

11755606_x_at

16859763

201422_PM_at

201422_at

3824876

3824877

3824878

3824879

3824880

3824881

3824882

3824883

3824885

3824886

3824887

3824888

3824889

39728_at

8026971

925_at

A_14_P122166

GE81622

GO:0002376

GO:0003824

GO:0005515

GO:0005576

GO:0005764

GO:0005773

GO:0005829

GO:0016491

GO:0016667

GO:0016671

GO:0019886

GO:0030054

GO:0042590

GO:0043202

GO:0043226

GO:0043231

GO:0048147

GO:0050821

HMNXSV003049776

ILMN_1807277

J03909_at

PH_hs_0001383

TC19002629.hg

g5453695_3p_at

Participates

as an output of

Expression of IFNG-stimulated genes (Homo sapiens)

Inferred To

IFI30 [lysosomal lumen] (Bos taurus)

IFI30 [lysosomal lumen] (Caenorhabditis elegans)

IFI30 [lysosomal lumen] (Canis familiaris)

IFI30 [lysosomal lumen] (Gallus gallus)

IFI30 [lysosomal lumen] (Sus scrofa)

Ifi30 [lysosomal lumen] (Mus musculus)

Ifi30 [lysosomal lumen] (Rattus norvegicus)

ifi30 [lysosomal lumen] (Danio rerio)

ifi30 [lysosomal lumen] (Xenopus tropicalis)

Dmel\CG9427 [lysosomal lumen] (Drosophila melanogaster)

Cross References

RefSeq

NP_006323.2

ENSEMBL

ENST00000407280, ENSP00000384886

OpenTargets

ENSG00000216490

HPA

ENSG00000216490-IFI30

PRO

P13284

Pharos - Targets

P13284

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53355 DAPK1	1	DAPK1 [cytosol] (R-HSA-418262)	0.725	6
UniProt:Q9BQ66 KR412			0.556	3
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:P22735 TGM1	3	TGM1 [cytosol] (R-HSA-6813756) TGM1 [cornified envelope] (R-HSA-8847706) TGM1 [plasma membrane] (R-HSA-6813757)	0.556	3
UniProt:Q7Z3V4 UBE3B	1	UBE3B [cytosol] (R-HSA-976043)	0.527	4
UniProt:Q8WUY9 DEPDC1B	1	DEPDC1B [cytosol] (R-HSA-200781)	0.527	3
UniProt:P35625 TIMP3	2	TIMP3 [extracellular region] (R-HSA-1430774) TIMP3 [platelet dense granule lumen] (R-HSA-8848904)	0.527	2
UniProt:Q5VYV7 SLX4I			0.527	2
UniProt:Q8WTQ1 DEFB104A	3	DEFB104A(?-72) [extracellular region] (R-HSA-975674) DEFB104A(?-72) [Golgi lumen] (R-HSA-1467258) DEFB104A(1-72) [Golgi lumen] (R-HSA-1467188)	0.527	2
UniProt:Q6AZZ1 TRIM68	1	TRIM68 [cytosol] (R-HSA-5624350)	0.527	3
UniProt:Q9BX10 GTPBP2	2	GTPBP2 [extracellular region] (R-HSA-8863001) GTPBP2 [platelet alpha granule lumen] (R-HSA-8862960)	0.527	3
UniProt:O43663 PRC1	1	PRC1 [cytosol] (R-HSA-264441)	0.527	2
UniProt:Q49AM3 TTC31			0.527	2
UniProt:Q9Y2R9 MRPS7	1	MRPS7 [mitochondrial inner membrane] (R-HSA-5368191)	0.527	3
UniProt:P49703 ARL4D			0.527	3
UniProt:Q5NDL2 EOGT			0.527	2
UniProt:Q9NZB2 F120A			0.527	4

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