Reactome | p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane]

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex

Stable Identifier

R-HSA-975130

Type

Complex

Species

Homo sapiens

Compartment

endosome membrane

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
15767370	Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction	J Exp Med	2005

Participants

components

Participant Of

input

Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9

output

First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9

Inferred To

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Bos taurus)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Canis familiaris)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Danio rerio)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Drosophila melanogaster)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Gallus gallus)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Mus musculus)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Rattus norvegicus)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Sus scrofa)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Taeniopygia guttata)

p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex [endosome membrane] (Xenopus tropicalis)

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