CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds GRB2:SOS1

Stable Identifier
R-HSA-9733330
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds GRB2:SOS1
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After an initial wave of phosphorylation of CSF1R, the stable GRB2:SOS1 complex transiently binds phospho-CSF1R (inferred from mouse homologs). GRB2 has been shown to bind phosphotyrosine-699, though another phosphotyrosine residue may be involved in transient binding of GRB2 (inferred from mouse homologs).
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Output
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as an event of
Inferred From
Csf1 dimer:p-Y559-Csf1r dimer binds Grb2:Sos1 (Mus musculus)
Authored
May, B  (2021-05-25)
Reviewed
Stanley, ER  (2022-10-06)
Created
May, B  (2021-06-03)
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