E Richard Stanley

 ORCID
https://orcid.org/0000-0002-2910-2065
Authored Reactions (4/4)
Date Identifier Reaction Reference
2022-10-06 R-MMU-9817994 Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1 binds Cbl BibTex
2022-10-06 R-HSA-9817983 CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds CBL BibTex
2022-10-06 R-MMU-9818009 Csf1 dimer:p-Y559-Csf1r dimer binds Src family kinases Fyn,Hck,Src,Yes1 BibTex
2022-10-06 R-HSA-9818010 CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer binds SRC family kinases FYN,HCK,SRC,YES1 BibTex
Reviewed Pathways (1/1)
Date Identifier Pathway Reference
2022-10-06 R-HSA-9680350 Signaling by CSF1 (M-CSF) in myeloid cells BibTex
Reviewed Reactions (15/24)
Date Identifier Reaction Reference
2022-10-06 R-HSA-9680388 CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine BibTex
2022-10-06 R-MMU-9682158 Csf1r-associated Plcg2 hydrolyzes phosphatidylcholine yielding choline phosphate and 1,2-diacylglycerol BibTex
2022-10-06 R-HSA-9680389 CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 BibTex
2022-10-06 R-MMU-9682182 Csf1r-associated PI3K phosphorylates phosphatidylinositol 4,5-bisphosphate BibTex
2022-10-06 R-HSA-9733316 p-Y-CBL autoubiquitinates and multiubiquitinates p-Y561-CSF1R in CSF1 dimer:p-Y561-CSF1R dimer:p-Y-CBL BibTex
2022-10-06 R-MMU-9763892 p-Y-Cbl autoubiquitinates and multiubiquitinates p-Y-559-Csf12 BibTex
2022-10-06 R-HSA-9733323 Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL BibTex
2022-10-06 R-MMU-9763891 Src family kinases phosphorylate Cbl in Csf1 dimer:p-Y559-Csf1r dimer:Cbl BibTex
2022-10-06 R-HSA-9680348 PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated BibTex
2022-10-06 R-MMU-9680646 Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated BibTex
2022-10-06 R-HSA-9733331 CSF1 dimer,IL34 dimer:p-Y561-CSF1R:GRB2:SOS1 dissociates yielding CSF1 dimer,IL34 dimer:p-Y561-CSF1R:SFK and GRB2:SOS1 BibTex
2022-10-06 R-MMU-9764150 Csf1 dimer:p-Y-559-Csf1r dimer:SFK:Grb2:Sos1 dissociates yielding Csf1 dimer:p-Y-559-Csf1r dimer:SFK and Grb2:Sos1 BibTex
2022-10-06 R-HSA-9680385 CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS BibTex
2022-10-06 R-MMU-9682572 Csf1r-associated Sos1 mediates exchange of GTP for GDP bound to Ras BibTex
2022-10-06 R-HSA-9733330 CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds GRB2:SOS1 BibTex
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