SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to HNRNPA1

Stable Identifier
R-HSA-9727869
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
cytosol
ReviewStatus
5/5
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SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to HNRNPA1
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Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) is involved in the packaging of pre-mRNA into hnRNP particles and the transport of poly(A) mRNA from the nucleus to the cytoplasm. SARS-CoV-1 nucleocapsid protein (N), the most abundant protein in SARS infection, binds to HNRNPA1. It is unknown whether this affects host mRNA transport or viral transcription (Luo et al, 2005).
Literature References
PubMed ID Title Journal Year
15862300 The nucleocapsid protein of SARS coronavirus has a high binding affinity to the human cellular heterogeneous nuclear ribonucleoprotein A1

Luo, H, Chen, Q, Chen, J, Chen, K, Shen, X, Jiang, H

FEBS Lett. 2005
Participants
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Output
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Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Cross References
Mondo
Authored
Stephan, R  (2021-04-16)
Reviewed
D'Eustachio, P  (2021-01-26)
Created
Stephan, R  (2021-04-19)
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