CARS1(2-606)-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9711974
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Cysteine--tRNA ligase, cytoplasmic ecNumber6.1.1.16/ecNumber, SYCC_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
13679433 Identification of CARS-ALK fusion in primary and metastatic lesions of an inflammatory myofibroblastic tumor

Helman, LJ, Schrump, DS, Tsokos, M, Arthur, DC, Pack, SD, Debelenko, LV

Lab Invest 2003
12112524 Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor

Marynen, P, De Wolf-Peeters, C, Pauwels, P, Somers, R, Hagemeijer, A, Pedeutour, F, Mentens, N, Cools, J, Maes, B, Wlodarska, I

Genes Chromosomes Cancer 2002
External Reference Information
External Reference
UniProt:P49589 CARS1
Gene Names
CARS1, CARS
Chain
initiator methionine:, chain:2-748
Reference Genes
BioGPS Gene:833 CARS1
CTD Gene:833 CARS1
dbSNP Gene:833 CARS1
ENSEMBL:ENSG00000110619 CARS
ENSEMBL_homo_sapiens_GENE:ENSG00000110619.18 CARS1
ENSEMBL_homo_sapiens_GENE:ENSG00000278191.4 CARS1
HGNC:1493 CARS1
KEGG Gene (Homo sapiens):833 CARS1
Monarch:833 CARS1
NCBI Gene:833 CARS1
OMIM:123859 CARS1
UCSC:P49589 CARS1
Reference Transcript
Other Identifiers
11716294_a_at
11737757_a_at
11737758_x_at
16734526
202402_PM_s_at
202402_s_at
212971_PM_at
212971_at
240983_PM_s_at
240983_s_at
3359530
3359531
3359532
3359533
3359534
3359535
3359537
3359540
3359545
3359546
3359552
3359556
3359558
3359559
3359560
3359562
3359563
3359564
3359567
3359570
3359571
3359573
3359574
3359575
3359576
3359579
3359581
3359585
3359595
40408_at
7945803
833
89954_at
A_24_P95439
GE57570
GO:0000049
GO:0000166
GO:0003723
GO:0003824
GO:0004812
GO:0004817
GO:0005515
GO:0005524
GO:0005737
GO:0005829
GO:0006399
GO:0006412
GO:0006418
GO:0006423
GO:0006520
GO:0016874
GO:0042802
GO:0042803
GO:0046872
GO:0140098
HMNXSV003011256
HMNXSV003028493
Hs.159604.1.A1_3p_a_at
Hs.197927.0.A1_3p_s_at
ILMN_1696066
ILMN_2367469
L06845_at
PH_hs_0023636
TC11001289.hg
TC11003010.hg
g10835050_3p_a_at
Participates
as a candidate of
as a component of
Other forms of this molecule
CARS [cytosol]
CARS1(2-606)-p-7Y-ALK(1058-1620) fusion [cytosol]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 607 from UniProt:Q9UM73 ALK
Coordinate
607
Disease
Cross References
RefSeq
COSMIC
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
HMDB Protein
Interactors (1)
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