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kinase domain ALK mutant dimers [plasma membrane]
Stable Identifier
R-HSA-9700082
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
Autophosphorylation of point mutants of ALK (Homo sapiens)
ALK point mutant dimers [plasma membrane] (Homo sapiens)
kinase domain ALK mutant dimers [plasma membrane] (Homo sapiens)
Ligand-independent dimerization of point mutants of ALK (Homo sapiens)
ALK point mutant dimers [plasma membrane] (Homo sapiens)
kinase domain ALK mutant dimers [plasma membrane] (Homo sapiens)
Participants
members
ALK M1166R dimer [plasma membrane]
(Homo sapiens)
ALK I1171N dimer [plasma membrane]
(Homo sapiens)
ALK F1174L dimer [plasma membrane]
(Homo sapiens)
ALK L1196M dimer [plasma membrane]
(Homo sapiens)
ALK L1196Q dimer [plasma membrane]
(Homo sapiens)
ALK L1198F dimer [plasma membrane]
(Homo sapiens)
ALK G1201E dimer [plasma membrane]
(Homo sapiens)
ALK R1275Q dimer [plasma membrane]
(Homo sapiens)
ALK L1122V dimer [plasma membrane]
(Homo sapiens)
ALK S1206C dimer [plasma membrane]
(Homo sapiens)
ALK V1180L dimer [plasma membrane]
(Homo sapiens)
ALK G1128A dimer [plasma membrane]
(Homo sapiens)
ALK E1384K dimer [plasma membrane]
(Homo sapiens)
candidates
ALK M1166N dimer [plasma membrane]
(Homo sapiens)
ALK M1166T dimer [plasma membrane]
(Homo sapiens)
ALK I1171T dimer [plasma membrane]
(Homo sapiens)
ALK F1174C dimer [plasma membrane]
(Homo sapiens)
ALK F1174I dimer [plasma membrane]
(Homo sapiens)
ALK F1174S dimer [plasma membrane]
(Homo sapiens)
ALK F1174V dimer [plasma membrane]
(Homo sapiens)
ALK G1201R dimer [plasma membrane]
(Homo sapiens)
ALK R1275* dimer [plasma membrane]
(Homo sapiens)
ALK R1275L dimer [plasma membrane]
(Homo sapiens)
ALK I1171S dimer [plasma membrane]
(Homo sapiens)
ALK G1128S dimer [plasma membrane]
(Homo sapiens)
ALK G1128V dimer [plasma membrane]
(Homo sapiens)
ALK Y1239H dimer [plasma membrane]
(Homo sapiens)
Participates
as a member of
ALK point mutant dimers [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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