Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ALK F1174L dimer [plasma membrane]
Stable Identifier
R-HSA-9699987
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
ALK mutants bind TKIs (Homo sapiens)
ALK mutants bind type I TKIs (Homo sapiens)
type I ALK-binding TKIs:type I-sensitive ALK mutants [cytosol] (Homo sapiens)
type I TKI sensitive ALK mutants [plasma membrane] (Homo sapiens)
NVP-TAE684-sensitive ALK mutants [cytosol] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
alectinib sensitve ALK mutants [plasma membrane] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
type I TKI sensitive ALK mutants [plasma membrane] (Homo sapiens)
NVP-TAE684-sensitive ALK mutants [cytosol] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
alectinib sensitve ALK mutants [plasma membrane] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
Drug resistance of ALK mutants (Homo sapiens)
ASP-3026-resistant ALK mutants (Homo sapiens)
ASP-3026- resistant ALK mutants don't bind ASP-3026 (Homo sapiens)
ASP3026-resistant ALK mutants [plasma membrane] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
ceritinib-resistant ALK mutants (Homo sapiens)
ceritinib-resistant ALK mutants don't bind ceritinib (Homo sapiens)
ceritinib-resistant ALK mutants [plasma membrane] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
crizotinib-resistant ALK mutants (Homo sapiens)
crizotinib-resistant ALK mutants don't bind crizotinib (Homo sapiens)
crizotinib resistant ALK mutants [plasma membrane] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
Autophosphorylation of point mutants of ALK (Homo sapiens)
ALK point mutant dimers [plasma membrane] (Homo sapiens)
kinase domain ALK mutant dimers [plasma membrane] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
Ligand-independent dimerization of point mutants of ALK (Homo sapiens)
ALK point mutant dimers [plasma membrane] (Homo sapiens)
kinase domain ALK mutant dimers [plasma membrane] (Homo sapiens)
ALK F1174L dimer [plasma membrane] (Homo sapiens)
Participants
components
x 2
ALK F1174L [plasma membrane]
(Homo sapiens)
Participates
as a member of
kinase domain ALK mutant dimers [plasma membrane] (Homo sapiens)
ceritinib-resistant ALK mutants [plasma membrane] (Homo sapiens)
crizotinib resistant ALK mutants [plasma membrane] (Homo sapiens)
ASP3026-resistant ALK mutants [plasma membrane] (Homo sapiens)
alectinib sensitve ALK mutants [plasma membrane] (Homo sapiens)
NVP-TAE684-sensitive ALK mutants [cytosol] (Homo sapiens)
Disease
Name
Identifier
Synonyms
neuroblastoma
DOID:769
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text