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Uncoating of SARS-CoV-1 Genome
Stable Identifier
R-HSA-9686709
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
cytosol
ReviewStatus
5/5
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
Attachment and Entry (Homo sapiens)
Uncoating of SARS-CoV-1 Genome (Homo sapiens)
General
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The viral nucleocapsid complex, released into the host cell cytosol, dissociates to release the viral RNA genome (Fung & Liu 2019).
Literature References
PubMed ID
Title
Journal
Year
31226023
Human Coronavirus: Host-Pathogen Interaction
Fung, TS
,
Liu, DX
Annu. Rev. Microbiol.
2019
Participants
Input
encapsidated SARS coronavirus genomic RNA (plus strand) [cytosol]
(Human SARS coronavirus)
Output
m7GpppA-capped SARS-CoV-1 genomic RNA (plus strand) [cytosol]
(Human SARS coronavirus)
x 150
SUMO1-K62-p-S177-N dimer [cytosol]
(Human SARS coronavirus)
Participates
as an event of
Attachment and Entry (Homo sapiens)
Orthologous Events
Uncoating of SARS-CoV-2 Genome (Homo sapiens)
Disease
Name
Identifier
Synonyms
severe acute respiratory syndrome
DOID:2945
SARS-CoV infection, SARS
Authored
Gillespie, ME (2020-05-05)
Reviewed
Acencio, ML (2020-05-27)
Mazein, A (2020-05-27)
Created
Gillespie, ME (2020-05-05)
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