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9b:PCBP2:MAVS [mitochondrial outer membrane]
Stable Identifier
R-HSA-9685193
Type
Complex
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
mitochondrial outer membrane
Synonyms
SARS-CoV-1 9b:PCBP2:MAVS
Locations in the PathwayBrowser
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1-host interactions (Homo sapiens)
SARS-CoV-1 activates/modulates innate immune responses (Homo sapiens)
SARS-CoV-1 9b binds MAVS and PCBP2 (Homo sapiens)
9b:PCBP2:MAVS [mitochondrial outer membrane] (Homo sapiens)
SARS-CoV-1 9b recruits ITCH to MAVS (Homo sapiens)
9b:PCBP2:MAVS [mitochondrial outer membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
25135833
SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome
Abu-Asab, M
,
Shi, CS
,
Kehrl, JH
,
Huang, NN
,
Shelhamer, JH
,
Qi, HY
,
Boularan, C
J. Immunol.
2014
Participants
components
9b homodimer [mitochondrial outer membrane]
(Human SARS coronavirus)
MAVS [mitochondrial outer membrane]
(Homo sapiens)
PCBP2 [cytosol]
(Homo sapiens)
Participates
as an input of
SARS-CoV-1 9b recruits ITCH to MAVS (Homo sapiens)
as an output of
SARS-CoV-1 9b binds MAVS and PCBP2 (Homo sapiens)
Disease
Name
Identifier
Synonyms
severe acute respiratory syndrome
DOID:2945
SARS-CoV infection, SARS
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