Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]
Stable Identifier
R-HSA-9665220
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction (Homo sapiens)
Signaling by ERBB2 in Cancer (Homo sapiens)
Constitutive Signaling by Overexpressed ERBB2 (Homo sapiens)
ERBB2 binds TKIs (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Trans-autophosphorylation of ERBB2 homodimer (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB2 (Homo sapiens)
Drug-mediated inhibition of ERBB2 signaling (Homo sapiens)
ERBB2 binds TKIs (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Participants
components
CDC37 [cytosol] (Homo sapiens)
ERBB2:TKIs [plasma membrane] (Homo sapiens)
ERBIN [plasma membrane] (Homo sapiens)
HSP90 [cytosol] (Homo sapiens)
Participant Of
output
ERBB2 binds TKIs
This entity regulates
Negatively
Trans-autophosphorylation of ERBB2 homodimer
Inferred To
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Bos taurus)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Danio rerio)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Drosophila melanogaster)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Gallus gallus)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Mus musculus)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Rattus norvegicus)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Xenopus tropicalis)
© 2020
Reactome
