IL10 gene produces IL10 protein

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R-HSA-9664346
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Reaction [omitted]
Species
Homo sapiens
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The Interleukin 10 (IL10) gene is located at chromosome 1q31-32. It encodes for a protein with the same name that acts as a pleiotropic cytokine expressed primarily by monocytes and to a smaller degree by lymphocytes. IL10 down-regulates the expression of Th1 cytokines, MHC class II and costimulatory molecules on macrophages (Eskdale et al. 1997).

Literature References
PubMed ID Title Journal Year
9162098 Mapping of the human IL10 gene and further characterization of the 5' flanking sequence

Eskdale, J, Kube, D, Tesch, H, Gallagher, G

Immunogenetics 1997
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