Calmodulin dissociates KRAS4B from the plasma membrane

Stable Identifier
R-HSA-9654521
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Ca2+/calmodulin-binding to KRAS4B dissociates it from the plasma membrane independent of nucleotide state (Firaz et al, 2005; Sidhu et al, 2003; Sperlich et al, 2016; reviewed in Shimashu et al, 2017).

Literature References
PubMed ID Title Journal Year
27410739 Regulation of K-Ras4B Membrane Binding by Calmodulin

Sperlich, B, Kapoor, S, Waldmann, H, Winter, R, Weise, K

Biophys. J. 2016
16043511 Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulin

Fivaz, M, Meyer, T

J. Cell Biol. 2005
28666118 RAS Proteins and Their Regulators in Human Disease

Simanshu, DK, Nissley, DV, McCormick, F

Cell 2017
12727204 Ca2+/calmodulin binds and dissociates K-RasB from membrane

Sidhu, RS, Clough, RR, Bhullar, RP

Biochem. Biophys. Res. Commun. 2003
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