RAS proteins undergo several processing steps during maturation including farnesylation, carboxy-terminal cleavage and carboxymethylation, among others. These steps are required for their membrane localization and function and ultimately for their ability to activate RAF (reviewed in Gysin et al, 2011; Ahearn et al, 2018).
McCormick, F, Salt, M, Young, A, Gysin, S
Philips, MR, Zhou, M, Ahearn, I
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