PtpA:Ub dephosphorylates p-Y133-VPS33B

Stable Identifier
R-HSA-9636439
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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PtpA:Ub dephosphorylates p-Y133-VPS33B
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The Mtb enzyme protein-tyrosine phosphatase (PtpA) catalyzes the dephosphorylation of human vacuolar protein sorting-associated protein 33B (VPS33B) (Bach et al. 2008).
Literature References
PubMed ID Title Journal Year
18474358 Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B

Bach, H, Papavinasasundaram, KG, Wong, D, Hmama, Z, Av-Gay, Y

Cell Host Microbe 2008
Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein tyrosine phosphatase activity of PtpA:Ub [cytosol]

Physical Entity
PtpA:Ub [cytosol] (Homo sapiens)
Activity
protein tyrosine phosphatase activity (GO:0004725)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Cross References
Mondo
Authored
Stephan, R  (2019-02-06)
Reviewed
Deffur, A  (2019-10-23)
Wilkinson, RJ  (2019-10-23)
Created
Koile, I  (2019-02-13)
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