NOS2 gene produces NOS2 protein

Stable Identifier
R-HSA-9636261
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NOS2 gene produces NOS2 protein
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The inducible nitric oxide synthase (NOS2) gene produces NOS2 protein. It is regulated by a NOS2 promotor, which itself is regulated by mycobacterial PPE family protein PPE2 (Bhat et al. 2017).

Literature References
PubMed ID Title Journal Year
28071726 The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production

Ghosh, S, Mukhopadhyay, S, Kotturu, SK, Bhat, KH, Srivastava, S

Sci Rep 2017
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
PPE2:NOS2 gene [nucleoplasm] (Homo sapiens)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Koile, I  (2019-02-12)
Cite Us!