Both GRB2 and SHC1 are recruited to autophosphorylated ERBB2 homodimers (Pickl and Ries 2009). It is assumed, by analogy to the behavior of normal ERBB2 heterodimers, that GRB2 is recruited to ERBB2 homodimers through SHC1, and that GRB2 is in complex with SOS1.
Pickl, M, Ries, CH
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