Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 heterodimers

Stable Identifier
R-HSA-1250486
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 heterodimers
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Phosphorylated SHC1 bound to phosphorylated ERBB2 dimers recruits GRB2:SOS1 complex (Xie et al. 1995).

Literature References
Participants
Input
Output
Participant Of
hasEvent
Inferred From
Recruitment of GRB2:Sos1 to P-Shc1:P-Erbb2mut complex (Homo sapiens)
Authored
Orlic-Milacic, M  (2011-11-04)
Reviewed
Neckers, LM  (2011-11-11)
Xu, W  (2011-11-11)
Created
Orlic-Milacic, M  (2011-04-21)
Cite Us!