Rama Krishna Kancha

 ORCID
https://orcid.org/0000-0001-8146-1551
Affiliation
Osmania University
Reviewed Pathways (15/16)
Date Identifier Pathway Reference
2019-10-25 R-HSA-9665737 Drug resistance in ERBB2 TMD/JMD mutants BibTex
2019-10-25 R-HSA-9665348 Signaling by ERBB2 ECD mutants BibTex
2019-10-25 R-HSA-9665686 Signaling by ERBB2 TMD/JMD mutants BibTex
2019-11-03 R-HSA-9652282 Drug-mediated inhibition of ERBB2 signaling BibTex
2019-09-16 R-HSA-1227990 Signaling by ERBB2 in Cancer BibTex
2019-09-16 R-HSA-9634285 Constitutive Signaling by Overexpressed ERBB2 BibTex
2019-09-16 R-HSA-9665230 Drug resistance in ERBB2 KD mutants BibTex
2019-09-16 R-HSA-9665244 Resistance of ERBB2 KD mutants to sapitinib BibTex
2019-09-16 R-HSA-9665245 Resistance of ERBB2 KD mutants to tesevatinib BibTex
2019-09-16 R-HSA-9665246 Resistance of ERBB2 KD mutants to neratinib BibTex
2019-09-16 R-HSA-9665247 Resistance of ERBB2 KD mutants to osimertinib BibTex
2019-09-16 R-HSA-9665249 Resistance of ERBB2 KD mutants to afatinib BibTex
2019-09-16 R-HSA-9665233 Resistance of ERBB2 KD mutants to trastuzumab BibTex
2019-09-16 R-HSA-9665250 Resistance of ERBB2 KD mutants to AEE788 BibTex
2019-09-16 R-HSA-9665251 Resistance of ERBB2 KD mutants to lapatinib BibTex
Reviewed Reactions (15/63)
Date Identifier Reaction Reference
2019-10-25 R-HSA-9665708 ERBB2 TMD/JMD mutants do not bind pertuzumab BibTex
2019-10-25 R-HSA-9665412 ERBB2 ECD mutants bind TKIs BibTex
2019-10-25 R-HSA-9665408 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 BibTex
2019-10-25 R-HSA-9665409 GRB2:SOS1 binds to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR BibTex
2019-10-25 R-HSA-9665411 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 BibTex
2019-10-25 R-HSA-9665410 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind PLCG1 BibTex
2019-10-25 R-HSA-9665404 RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 BibTex
2019-10-25 R-HSA-9665413 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR recruit GRB2:SOS1 through SHC1 BibTex
2019-10-25 R-HSA-9665405 ERBB2 ECD mutants bind trastuzumab BibTex
2019-10-25 R-HSA-9665406 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 BibTex
2019-10-25 R-HSA-9665416 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind SHC1 BibTex
2019-10-25 R-HSA-9665407 PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 BibTex
2019-10-25 R-HSA-9665415 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K BibTex
2019-10-25 R-HSA-9665417 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind GRB2:GAB1 BibTex
2019-10-25 R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate BibTex