Phosphorylation of LBR (lamin B receptor) at serine residue S71 drives binding of LBR to KPNB1 (importin beta) (Lu et al. 2010). This prevents premature association of nascent nuclear membranes with chromatin in anaphase (Tseng and Chen 2011). Dephosphorylation of this site is suggested to promote NE reassembly (Tseng and Chen 2011).
Lu, X, Shi, Y, Lu, Q, Ma, Y, Luo, J, Wang, Q, Ji, J, Jiang, Q, Zhang, C
© 2021 Reactome
