EGFR:EGF-like ligands [plasma membrane]

Stable Identifier
R-HSA-9624419
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
27153536 Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling

Runkle, KB, Kharbanda, A, Stypulkowski, E, Cao, XJ, Wang, W, Garcia, BA, Witze, ES

Mol. Cell 2016
12297049 Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

Garrett, TP, McKern, NM, Lou, M, Elleman, TC, Adams, TE, Lovrecz, GO, Zhu, HJ, Walker, F, Frenkel, MJ, Hoyne, PA, Jorissen, RN, Nice, EC, Burgess, AW, Ward, CW

Cell 2002
7679104 Amphiregulin induces tyrosine phosphorylation of the epidermal growth factor receptor and p185erbB2. Evidence that amphiregulin acts exclusively through the epidermal growth factor receptor at the surface of human epithelial cells

Johnson, GR, Kannan, B, Shoyab, M, Stromberg, K

J. Biol. Chem. 1993
2790960 Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

Chen, WS, Lazar, CS, Lund, KA, Welsh, JB, Chang, CP, Walton, GM, Der, CJ, Wiley, HS, Gill, GN, Rosenfeld, MG

Cell 1989
12421825 Proximal events in signaling by plasma membrane estrogen receptors

Razandi, M, Pedram, A, Park, ST, Levin, ER

J. Biol. Chem. 2003
9419975 Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4

Komurasaki, T, Toyoda, H, Uchida, D, Morimoto, S

Oncogene 1997
8144591 Recombinant human betacellulin. Molecular structure, biological activities, and receptor interaction

Watanabe, T, Shintani, A, Nakata, M, Shing, Y, Folkman, J, Igarashi, K, Sasada, R

J. Biol. Chem. 1994
20837704 Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor

Lu, C, Mi, LZ, Grey, MJ, Zhu, J, Graef, E, Yokoyama, S, Springer, TA

Mol. Cell. Biol. 2010
15611079 Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

Kochupurakkal, BS, Harari, D, Di-Segni, A, Maik-Rachline, G, Lyass, L, Gur, G, Kerber, G, Citri, A, Lavi, S, Eilam, R, Chalifa-Caspi, V, Eshhar, Z, Pikarsky, E, Pinkas-Kramarski, R, Bacus, SS, Yarden, Y

J. Biol. Chem. 2005
Participants
Participant Of
Inferred To