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RAP1:GTP:activated BRAF dimer [endosome membrane]
Stable Identifier
R-HSA-9610130
Type
Complex
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
Frs2-mediated activation (Homo sapiens)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Homo sapiens)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
BRAF autophosphorylates downstream of RAP1 and NGF (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
Dissociation of phosphorylated MAP2Ks and MAPKs (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
Participants
components
x 2
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Homo sapiens)
RAP1:GTP [endosome membrane]
(Homo sapiens)
Participates
as an input of
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Homo sapiens)
as an output of
BRAF autophosphorylates downstream of RAP1 and NGF (Homo sapiens)
Dissociation of phosphorylated MAP2Ks and MAPKs (Homo sapiens)
as a component of
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Homo sapiens)
Inferred To
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Caenorhabditis elegans)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Canis familiaris)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Danio rerio)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Dictyostelium discoideum)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Gallus gallus)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Mus musculus)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Rattus norvegicus)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Sus scrofa)
RAP1:GTP:activated BRAF dimer [endosome membrane]
(Xenopus tropicalis)
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