Reactome | BAX activation is stimulated by NTRK3(495-641) and NELFB

BAX activation is stimulated by NTRK3(495-641) and NELFB

Stable Identifier

R-HSA-9603598

Type

Reaction [BlackBoxEvent]

Species

Homo sapiens

Compartment

cytosol, mitochondrial outer membrane

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BAX activation is stimulated by NTRK3(495-641) and NELFB

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The complex of NTRK3 (TRKC) killer fragment (KF) and NELFB (COBRA1) stimulates BAX activation through an unknown mechanism. This is followed by BAX-dependent cytochrome C release and apoptosome-dependent cell death (Ichim et al. 2013).

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