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K63-linked polyUb p-IRAK1:TRAF6 [cytosol]
Stable Identifier
R-HSA-937043
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
IRAK1 recruits IKK complex (Homo sapiens)
NEMO subunit of IKK complex binds to activated IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Pellino ubiquitinates hp-IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
IRAK1 recruits IKK complex (Homo sapiens)
NEMO subunit of IKK complex binds to activated IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Pellino ubiquitinates hp-IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
IRAK1 recruits IKK complex (Homo sapiens)
NEMO subunit of IKK complex binds to activated IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Pellino ubiquitinates hp-IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
IRAK1 recruits IKK complex (Homo sapiens)
NEMO subunit of IKK complex binds to activated IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Pellino ubiquitinates hp-IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
IRAK1 recruits IKK complex (Homo sapiens)
NEMO subunit of IKK complex binds to activated IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol] (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Pellino ubiquitinates hp-IRAK1 (Homo sapiens)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Homo sapiens)
Participants
components
K63polyUb-hp-IRAK1 [cytosol] (Homo sapiens)
TRAF6 [cytosol] (Homo sapiens)
Participant Of
hasComponent
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol]
input
NEMO subunit of IKK complex binds to activated IRAK1
output
Pellino ubiquitinates hp-IRAK1
Inferred To
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Bos taurus)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Canis familiaris)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Danio rerio)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Dictyostelium discoideum)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Drosophila melanogaster)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Mus musculus)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Rattus norvegicus)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Sus scrofa)
K63-linked polyUb p-IRAK1:TRAF6 [cytosol] (Xenopus tropicalis)
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