Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
TRAF2, TRAF6 [cytosol]
Stable Identifier
R-HSA-918188
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
TRAF6 mediated IRF7 activation (Homo sapiens)
Phosphorylation and release of IRF7 (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKKi [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKKi:IRF7 [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKKi [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
Recruitment of IRF7 to TRAF6 (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKKi [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKKi:IRF7 [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKKi [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
Recruitment of TANK to TRAF6 (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:TBK1/IKKi [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
Recruitment of TRAF6/TRAF2 to IPS-1 (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
TRAF6 mediated NF-kB activation (Homo sapiens)
Activation of IKK by MEKK1 (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:MEKK1 [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
Interaction of MEKK1 with TRAF6 (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:MEKK1 [mitochondrial outer membrane] (Homo sapiens)
dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane] (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP4 deubiquitinate TRAF2,TRAF6 (Homo sapiens)
TRAF2, TRAF6 [cytosol] (Homo sapiens)
Participants
members
TRAF2 [cytosol] (Homo sapiens)
TRAF6 [cytosol] (Homo sapiens)
Participant Of
output
USP4 deubiquitinate TRAF2,TRAF6
input
Recruitment of TRAF6/TRAF2 to IPS-1
hasComponent
IPS-1:TRAF2/TRAF6 [mitochondrial outer membrane]
Inferred To
TRAF6 [cytosol] (Drosophila melanogaster)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Dictyostelium discoideum)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Gallus gallus)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Plasmodium falciparum)
TRAF2, TRAF6 [cytosol] (Bos taurus)
TRAF2, TRAF6 [cytosol] (Canis familiaris)
TRAF2, TRAF6 [cytosol] (Danio rerio)
TRAF2, TRAF6 [cytosol] (Mus musculus)
TRAF2, TRAF6 [cytosol] (Rattus norvegicus)
TRAF2, TRAF6 [cytosol] (Sus scrofa)
TRAF2, TRAF6 [cytosol] (Xenopus tropicalis)
© 2020
Reactome
