TYSND1 cleaves ACAA1

Stable Identifier
R-HSA-9033529
Type
Reaction [transition]
Species
Homo sapiens
Compartment
peroxisomal matrix
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TYSND1 cleaves ACAA1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The trypsin-like serine-type endopeptidase TYSND1 cleaves ACAA1 between amino acid residues 26 and 27, yielding ACAA1(1-26) and ACAA1(27-424) (Okumoto et al. 2011). In mice, knockout of Tysnd1 causes reduced localization of Acaa1 to the peroxisome.

Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

serine-type endopeptidase activity of TYSND1 [peroxisomal matrix]

Physical Entity
TYSND1 [peroxisomal matrix] (Homo sapiens)
Activity
serine-type endopeptidase activity (GO:0004252)
Inferred From
Tysnd1 cleaves Acaa1a (Mus musculus)
Authored
May, B  (2017-12-22)
Reviewed
Van Veldhoven, PP  (2018-02-13)
Fransen, M  (2018-02-13)
Azevedo, JE  (2018-03-12)
Created
May, B  (2017-12-22)
Cite Us!