TYSND1 cleaves ACAA1

Stable Identifier
R-HSA-9033529
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The trypsin-like serine-type endopeptidase TYSND1 cleaves ACAA1 between amino acid residues 26 and 27, yielding ACAA1(1-26) and ACAA1(27-424) (Okumoto et al. 2011). In mice, knockout of Tysnd1 causes reduced localization of Acaa1 to the peroxisome.

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Catalyst Activity
Catalyst Activity
Title
serine-type endopeptidase activity of TYSND1 [peroxisomal matrix]
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