FKBP5 gene expression is inhibited by MECP2

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R-HSA-9022728
Type
Reaction [omitted]
Species
Homo sapiens
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Based on studies in mice, MECP2 directly inhibits transcription of the FKBP5 gene, encoding peptidyl-prolyl cis-trans isomerase involved in trafficking of glucocorticoid receptors. Fkbp5 level is increased in Mecp2 null mice (Nuber et al. 2005, Urdinguio et al. 2008).

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