IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane]

Stable Identifier
R-HSA-8950331
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
12734330 Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment

Takeda, A, Hamano, S, Yamanaka, A, Hanada, T, Ishibashi, T, Mak, TW, Yoshimura, A, Yoshida, H

J. Immunol. 2003
18389480 IL-12, IL-23, and IL-27 enhance human beta-defensin-2 production in human keratinocytes

Kanda, N, Watanabe, S

Eur. J. Immunol. 2008
14764690 WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

Pflanz, S, Hibbert, L, Mattson, J, Rosales, R, Vaisberg, E, Bazan, JF, Phillips, JH, McClanahan, TK, de Waal Malefyt, R, Kastelein, RA

J Immunol 2004
Participants
components
Participates
as an input of
as an output of
as a component of
Inferred To
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Bos taurus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Canis familiaris)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Mus musculus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Rattus norvegicus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Sus scrofa)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Xenopus tropicalis)
Cite Us!