Reactome | RIOX2 [nucleoplasm]

RIOX2 [nucleoplasm]

Stable Identifier

R-HSA-8942439

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

MINA, Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, MINA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8IUF8 RIOX2

Gene Names

RIOX2, MDIG, MINA, MINA53, NO52

Chain

chain:1-465

Reference Genes

BioGPS Gene:84864 RIOX2

COSMIC (genes):RIOX2 RIOX2

CTD Gene:84864 RIOX2

dbSNP Gene:84864 RIOX2

ENSEMBL:ENSG00000170854 RIOX2

HGNC:19441 RIOX2

KEGG:hsa:84864 RIOX2

Monarch:84864 RIOX2

NCBI Gene:84864 RIOX2

OMIM:612049 RIOX2

UCSC:Q8IUF8 RIOX2

Reference Transcript

Other Identifiers

11727083_a_at

11739591_s_at

11739592_a_at

1554774_PM_at

1554774_at

16956621

213188_PM_s_at

213188_s_at

213189_PM_at

213189_at

229132_PM_at

229132_at

2685772

2685773

2685774

2685775

2685777

2685778

2685779

2685780

2685781

2685782

2685783

2685784

2685785

2685786

2685787

2685789

2685790

2685791

2685793

2685795

2685796

2685801

2685804

2685805

2685806

2685807

2685808

2685809

2685810

2685811

2685812

2685813

34662_at

65108_at

8089040

84864

A_23_P91827

A_24_P388570

A_32_P208964

A_33_P3314146

GE59619

GO:0003714

GO:0003824

GO:0005506

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005730

GO:0005829

GO:0006325

GO:0006338

GO:0006355

GO:0016491

GO:0016706

GO:0032452

GO:0032453

GO:0036139

GO:0042254

GO:0042802

GO:0045892

GO:0046872

GO:0051213

GO:0051864

GO:0140096

HMNXSV003004779

HMNXSV003052048

Hs.23294.1.S1_3p_at

Hs.23294.1.S2_3p_at

Hs.72465.0.A1_3p_at

Hs2.23294.2.S1_3p_s_at

ILMN_1689624

ILMN_2322986

PH_hs_0002052

TC03001599.hg

TC03002999.hg

Participates

as a component of

RIOX2:Fe2+ [nucleoplasm] (Homo sapiens)

as a member of

KDM4A, KDM4B, KDM4C, KDM4D, MINA [nucleoplasm] (Homo sapiens)

Inferred To

Riox2 [nucleoplasm] (Mus musculus)

Riox2 [nucleoplasm] (Rattus norvegicus)

RIOX2 [nucleoplasm] (Bos taurus)

RIOX2 [nucleoplasm] (Canis familiaris)

riox2 [nucleoplasm] (Danio rerio)

MINA [nucleoplasm] (Gallus gallus)

MINA [nucleoplasm] (Sus scrofa)

jcdg [nucleoplasm] (Dictyostelium discoideum)

Cross References

RefSeq

XP_054204120.1, NP_694822.2, NP_116167.3, XP_047305041.1, NP_001035998.1, NP_001248758.1, XP_047305043.1, XP_005247895.1

OpenTargets

ENSG00000170854

ENSEMBL

ENSP00000377748, ENST00000394198, ENST00000360258, ENST00000514314, ENSP00000424955, ENST00000333396, ENSG00000170854, ENSP00000328251, ENSP00000353395

HPA

ENSG00000170854-RIOX2

GeneCards

RIOX2

PRO

Q8IUF8

Pharos - Targets

Q8IUF8

GlyGen

Q8IUF8

PDB

4BU2, 2XDV, 4BXF

HMDB Protein

HMDBP11829

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.527	2
UniProt:P62280 RPS11	2	RPS11 [cytosol] (R-HSA-72327) RPS11 [nucleoplasm] (R-HSA-6791212)	0.483	2