Reactome | VCPIP1 [endoplasmic reticulum lumen]

VCPIP1 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8940103

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Deubiquitinating protein VCIP135 ecNumber3.4.19.12/ecNumber, VCIP1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96JH7 VCPIP1

Gene Names

VCPIP1, KIAA1850, VCIP135

Chain

chain:1-1222

Reference Genes

BioGPS Gene:80124 VCPIP1

COSMIC (genes):VCPIP1 VCPIP1

CTD Gene:80124 VCPIP1

dbSNP Gene:80124 VCPIP1

ENSEMBL:ENSG00000175073 VCPIP1

HGNC:30897 VCPIP1

Monarch:80124 VCPIP1

NCBI Gene:80124 VCPIP1

OMIM:611745 VCPIP1

UCSC:Q96JH7 VCPIP1

Reference Transcript

RefSeq:NM_025054.4 VCPIP1

Other Identifiers

11739800_a_at

11739801_x_at

11739802_at

11752069_a_at

11759319_at

1556227_PM_at

1556227_at

1556228_PM_a_at

1556228_a_at

17077848

219810_PM_at

219810_at

234988_PM_at

234988_at

3138810

3138812

3138813

3138814

3138816

3138819

3138820

3138821

3138822

3138823

3138824

3417040

42761_at

60001_at

80124

8151118

A_23_P256445

A_32_P74366

A_33_P3223467

GE763660

GE87281

GO:0003824

GO:0004843

GO:0005515

GO:0005634

GO:0005737

GO:0005783

GO:0005788

GO:0005794

GO:0005795

GO:0006281

GO:0006508

GO:0006974

GO:0007030

GO:0008234

GO:0016320

GO:0016567

GO:0016579

GO:0016787

GO:0035871

GO:0043226

GO:0061024

GO:0071108

GO:0090168

GO:0106300

GO:0140096

GO:1905634

HMNXSV003000510

HMNXSV003045050

Hs.146327.0.A1_3p_at

Hs2.159225.1.S1_3p_s_at

ILMN_1682180

PH_hs_0009674

TC08001288.hg

TC08002366.hg

g13376584_3p_at

Participates

as an input of

CDK1 phosphorylates VCPIP1 (Homo sapiens)

Other forms of this molecule

p-S131-VCPIP1 [endoplasmic reticulum lumen]

Inferred To

vcpip1 [endoplasmic reticulum lumen] (Xenopus tropicalis)

VCPIP1 [endoplasmic reticulum lumen] (Bos taurus)

VCPIP1 [endoplasmic reticulum lumen] (Canis familiaris)

VCPIP1 [endoplasmic reticulum lumen] (Gallus gallus)

VCPIP1 [endoplasmic reticulum lumen] (Sus scrofa)

Vcpip1 [endoplasmic reticulum lumen] (Mus musculus)

Vcpip1 [endoplasmic reticulum lumen] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000309031, ENST00000310421

OpenTargets

ENSG00000175073

IntEnz

3.4.19.12

HPA

ENSG00000175073-VCPIP1

PRO

Q96JH7

Pharos - Targets

Q96JH7

GlyGen

Q96JH7

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96KN8 PLAAT5	1	HRASLS5 [cytosol] (R-HSA-8858534)	0.589	3
UniProt:Q96JI7 SPTCS			0.547	2
UniProt:P55072 VCP	8	VCP [cytosol] (R-HSA-1181251) VCP [secretory granule lumen] (R-HSA-6801039) VCP [extracellular region] (R-HSA-6806191) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [nucleoplasm] (R-HSA-5643745) VCP [endoplasmic reticulum membrane] (R-HSA-8943105) Me3K315-VCP [cytosol] (R-HSA-8932209)	0.527	2
UniProt:Q8IYX4 DND1			0.527	2
UniProt:Q6P9H4 CNKR3			0.527	3
UniProt:Q96CS3 FAF2	3	FAF2 [cytosol] (R-HSA-6781921) FAF2 [extracellular region] (R-HSA-6806183) FAF2 [azurophil granule lumen] (R-HSA-6799138)	0.527	2
UniProt:Q9H2C0 GAN	1	GAN [cytosol] (R-HSA-976014)	0.527	3
UniProt:P55345 ANM2			0.527	3
UniProt:Q9BZV1 UBXN6			0.527	2
UniProt:O95897 NOE2			0.527	2
UniProt:Q9H063 MAF1	3	p-S60,S68,S75-MAF1 [cytosol] (R-HSA-8944455) MAF1 [cytosol] (R-HSA-8944460) MAF1 [nucleoplasm] (R-HSA-8944422)	0.527	2