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GGC-RAB40A [cytosol]
Stable Identifier
R-HSA-8874021
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ras-related protein Rab-40A, RB40A_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
CHMs:GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
GGC-RAB40A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WXH6 RAB40A
Gene Names
RAB40A
Chain
chain:1-274, propeptide:275-277
Reference Genes
BioGPS Gene:142684 RAB40A
COSMIC (genes):RAB40A RAB40A
CTD Gene:142684 RAB40A
dbSNP Gene:142684 RAB40A
ENSEMBL:ENSG00000172476 RAB40A
HGNC:18283 RAB40A
KEGG:hsa:142684 RAB40A
Monarch:142684 RAB40A
NCBI Gene:142684 RAB40A
OMIM:301065 RAB40A
UCSC:Q8WXH6 RAB40A
Reference Transcript
RefSeq:NM_080879.2 RAB40A
RefSeq:XM_011530872.2 RAB40A
RefSeq:XM_005262083.4 RAB40A
Other Identifiers
107_at
108_g_at
11733769_s_at
11734388_s_at
11745618_s_at
11759133_at
142684
17112975
215782_PM_at
215782_at
217589_PM_at
217589_at
33477_at
3775215
3775225
3985427
3985428
3985429
3985430
3985432
3985433
4016486
4016487
4016488
4016489
4016490
4016491
4016492
4016493
4016494
4016495
4016496
4016497
4016501
8174246
ADDON002798.hg
A_32_P88719
GO:0003824
GO:0003924
GO:0005525
GO:0005768
GO:0005794
GO:0005811
GO:0005886
GO:0006887
GO:0008021
GO:0009306
GO:0016192
GO:0016567
GO:0016787
GO:0031410
GO:0035556
GO:0043226
HMNXSV003057609
Hs.248013.0.S1_3p_s_at
Hs.248013.0.S1_3p_x_at
Hs.27453.0.S1_3p_at
ILMN_1819492
ILMN_1850626
ILMN_2218068
TC0X001240.hg
Participates
as a candidate of
GGC-RABs [cytosol] (Homo sapiens)
Other forms of this molecule
RAB40A [cytosol]
Inferred To
Homologues of GGC-RAB40A [cytosol]
(Dictyostelium discoideum)
Homologues of GGC-RAB40A [cytosol]
(Schizosaccharomyces pombe)
GGC-RAB40A [cytosol]
(Dictyostelium discoideum)
GGC-RAB40A [cytosol]
(Gallus gallus)
GGC-RAB40A [cytosol]
(Mus musculus)
GGC-RAB40A [cytosol]
(Saccharomyces cerevisiae)
GGC-RAB40A [cytosol]
(Schizosaccharomyces pombe)
Rab40b [cytosol]
(Rattus norvegicus)
Rab40 [cytosol]
(Drosophila melanogaster)
RAB40B [cytosol]
(Bos taurus)
RAB40B [cytosol]
(Canis familiaris)
RAB40B [cytosol]
(Sus scrofa)
rab40b [cytosol]
(Xenopus tropicalis)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 274
Coordinate
274
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
ENSEMBL
ENST00000304236
,
ENSP00000361716
,
ENST00000372633
,
ENSG00000172476
,
ENSP00000305648
OpenTargets
ENSG00000172476
GeneCards
RAB40A
HPA
ENSG00000172476-RAB40A
PRO
Q8WXH6
Pharos - Targets
Q8WXH6
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15369 ELOC
2
ELOC [cytosol]
(R-HSA-180535)
TCEB1 [nucleoplasm]
(R-HSA-112422)
0.527
2
UniProt:Q93034 CUL5
2
CUL5 [cytosol]
(R-HSA-180528)
G76-NEDD8-K724-CUL5 [cytosol]
(R-HSA-8952014)
0.527
3
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