Reactome | GGC-RAB25 [cytosol]

GGC-RAB25 [cytosol]

Stable Identifier

R-HSA-8873780

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ras-related protein Rab-25, RAB25_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P57735 RAB25

Gene Names

RAB25, CATX8

Chain

chain:1-210, propeptide:211-213

Reference Genes

BioGPS Gene:57111 RAB25

COSMIC (genes):RAB25 RAB25

CTD Gene:57111 RAB25

dbSNP Gene:57111 RAB25

ENSEMBL:ENSG00000132698 RAB25

HGNC:18238 RAB25

KEGG:hsa:57111 RAB25

Monarch:57111 RAB25

NCBI Gene:57111 RAB25

OMIM:612942 RAB25

UCSC:P57735 RAB25

Reference Transcript

RefSeq:NM_020387.4 RAB25

Other Identifiers

11729639_at

16671901

218186_PM_at

218186_at

2361258

2361259

2361262

2361263

2361264

2361265

2361266

2361267

2361268

2361269

2361270

48963_at

57111

7906079

A_23_P115091

GE82535

GE88647

GO:0000166

GO:0003382

GO:0003924

GO:0003925

GO:0005515

GO:0005525

GO:0005768

GO:0005794

GO:0005886

GO:0006887

GO:0008284

GO:0010634

GO:0015031

GO:0016020

GO:0016192

GO:0016787

GO:0031143

GO:0031260

GO:0031268

GO:0031410

GO:0031489

GO:0042995

GO:0055037

GO:0060627

GO:0070062

GO:0098772

ILMN_1791826

PH_hs_0009084

TC01001311.hg

g9966860_3p_at

Participates

as a candidate of

GGC-RABs [cytosol] (Homo sapiens)

Other forms of this molecule

RAB25 [cytosol]

Inferred To

Rab11 [cytosol] (Drosophila melanogaster)

GGC-RAB25 [cytosol] (Canis familiaris)

YPT32 [cytosol] (Saccharomyces cerevisiae)

ypt3 [cytosol] (Schizosaccharomyces pombe)

rab-11.2 [cytosol] (Caenorhabditis elegans)

rab25 [cytosol] (Xenopus tropicalis)

rab25b [cytosol] (Danio rerio)

Homologues of GGC-RAB25 [cytosol] (Caenorhabditis elegans)

Homologues of GGC-RAB25 [cytosol] (Saccharomyces cerevisiae)

rab-11.1 [cytosol] (Caenorhabditis elegans)

rab11A [cytosol] (Dictyostelium discoideum)

RAB25 [cytosol] (Bos taurus)

RAB25 [cytosol] (Gallus gallus)

RAB25 [cytosol] (Sus scrofa)

Rab25 [cytosol] (Mus musculus)

Rab25 [cytosol] (Rattus norvegicus)

YPT31 [cytosol] (Saccharomyces cerevisiae)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 209

Coordinate

209

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 210

Coordinate

210

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

RefSeq

NP_065120.2

ENSEMBL

ENST00000361084, ENSP00000354376, ENSG00000132698

OpenTargets

ENSG00000132698

IntEnz

3.6.5.2

GeneCards

RAB25

HPA

ENSG00000132698-RAB25

PRO

P57735

Pharos - Targets

P57735

PDB

3TSO, 2OIL

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P15056 BRAF	20	p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620)	0.553	4

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