Reactome | PLEKHA1 [plasma membrane]

PLEKHA1 [plasma membrane]

Stable Identifier

R-HSA-8870328

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Pleckstrin homology domain-containing family A member 1, PKHA1_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism (Homo sapiens)

- Metabolism of lipids (Homo sapiens)
  - Phospholipid metabolism (Homo sapiens)
    - PI Metabolism (Homo sapiens)
      - Synthesis of PIPs at the plasma membrane (Homo sapiens)
        
        PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Homo sapiens)
        
        PTPN13:PLEKHA1,2 [plasma membrane] (Homo sapiens)
        
        PTPN13:PLEKHA1 [plasma membrane] (Homo sapiens)
        
        PLEKHA1 [plasma membrane] (Homo sapiens)
        
        PTPN13:PLEKHA1,2:PIP2 [plasma membrane] (Homo sapiens)
        
        PTPN13:PLEKHA1,2 [plasma membrane] (Homo sapiens)
        
        PTPN13:PLEKHA1 [plasma membrane] (Homo sapiens)
        
        PLEKHA1 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9HB21 PLEKHA1

Gene Names

PLEKHA1, TAPP1

Chain

chain:1-404

Reference Genes

BioGPS Gene:59338 PLEKHA1

COSMIC (genes):PLEKHA1 PLEKHA1

CTD Gene:59338 PLEKHA1

dbSNP Gene:59338 PLEKHA1

ENSEMBL:ENSG00000107679 PLEKHA1

HGNC:14335 PLEKHA1

Monarch:59338 PLEKHA1

NCBI Gene:59338 PLEKHA1

OMIM:607772 PLEKHA1

UCSC:Q9HB21 PLEKHA1

Reference Transcript

Other Identifiers

11722965_s_at

11722966_a_at

11757389_s_at

16710095

16710120

219024_PM_at

219024_at

226247_PM_at

226247_at

3268275

3268276

3268278

3268279

3268280

3268282

3268283

3268286

3268288

3268290

3268294

3268295

3268296

3268298

3268299

3268300

3268301

3268303

3268304

3268305

3268306

3268307

3268308

3268312

3268313

3268314

3268318

3268319

3268320

3268322

48547_at

48802_s_at

59338

64035_at

72112_at

72972_at

78577_at

7931081

A_14_P104000

A_14_P117913

A_23_P115792

A_24_P269814

GE525788

GE56633

GE56985

GO:0001553

GO:0002376

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0006629

GO:0007283

GO:0008209

GO:0008210

GO:0008289

GO:0008585

GO:0009791

GO:0016020

GO:0022414

GO:0030154

GO:0030165

GO:0031529

GO:0032587

GO:0033327

GO:0035264

GO:0043226

GO:0043325

GO:0043491

GO:0045184

GO:0048008

GO:0048705

GO:0048856

GO:0050853

GO:0051898

GO:0060021

GO:0060325

GO:0070062

GO:0070301

HMNXSV003004016

HMNXSV003021278

HMNXSV003024888

Hs.287830.0.A1_3p_at

ILMN_1662839

ILMN_1828754

ILMN_2394250

PH_hs_0014922

PH_hs_0018075

PH_hs_0041178

TC10000886.hg

TC10000887.hg

g11055985_3p_at

Participates

as a component of

PTPN13:PLEKHA1 [plasma membrane] (Homo sapiens)

Inferred To

Plekha1 [plasma membrane] (Mus musculus)

Plekha1 [plasma membrane] (Rattus norvegicus)

PLEKHA1 [plasma membrane] (Bos taurus)

PLEKHA1 [plasma membrane] (Canis familiaris)

PLEKHA1 [plasma membrane] (Gallus gallus)

PLEKHA1 [plasma membrane] (Sus scrofa)

Cross References

ENSEMBL

ENST00000368990, ENST00000433307, ENSP00000376547, ENSP00000357986, ENSP00000394416, ENST00000368988, ENSP00000357984, ENST00000392799

OpenTargets

ENSG00000107679

HPA

ENSG00000107679-PLEKHA1

PRO

Q9HB21

Pharos - Targets

Q9HB21

GlyGen

Q9HB21

PDB

1EAZ

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75807 PPP1R15A	1	PPP1R15A [cytosol] (R-HSA-178231)	0.527	2
UniProt:Q9P0V3 SH3BP4	1	SH3BP4 [cytosol] (R-HSA-8866227)	0.508	2