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EGF [clathrin-coated endocytic vesicle membrane]
Stable Identifier
R-HSA-8869086
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-coated endocytic vesicle membrane
Synonyms
Epidermal Growth Factor
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin recruits auxilins to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Dissociation of clathrin-associated proteins (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
RAB5 and GAPVD1 bind AP-2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01133 EGF
Gene Names
EGF
Chain
signal peptide:1-22, chain:23-1207, chain:971-1023
Reference Genes
BioGPS Gene:1950 EGF
COSMIC (genes):EGF EGF
CTD Gene:1950 EGF
dbSNP Gene:1950 EGF
ENSEMBL:ENSG00000138798 EGF
ENSEMBL_homo_sapiens_GENE:ENSG00000138798.13 EGF
HGNC:3229 EGF
KEGG Gene (Homo sapiens):1950 EGF
Monarch:1950 EGF
NCBI Gene:1950 EGF
OMIM:131530 EGF
UCSC:P01133 EGF
Reference Transcript
RefSeq:NM_001178130.2 EGF
RefSeq:NM_001963.5 EGF
RefSeq:NM_001178131.2 EGF
Other Identifiers
11727113_at
11751935_a_at
11756749_a_at
1542_at
16969729
1950
206254_PM_at
206254_at
2739313
2739314
2739315
2739316
2739324
2739325
2739326
2739327
2739328
2739335
2739336
2739338
2739339
2739340
2739341
2739342
2739343
2739344
2739346
2739347
2739348
2739350
2739353
2739354
2739357
2739358
2739359
2739360
2739364
2739365
2739367
2739368
2739369
2739370
2739371
2739372
2739373
53431_at
8096845
A_14_P108123
A_14_P113507
A_14_P120827
A_23_P155979
GE58272
GE894110
GO:0000278
GO:0001525
GO:0001938
GO:0002092
GO:0005085
GO:0005154
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005765
GO:0005773
GO:0005886
GO:0005975
GO:0006351
GO:0006355
GO:0007173
GO:0008083
GO:0008283
GO:0008284
GO:0010595
GO:0010628
GO:0010800
GO:0016020
GO:0016192
GO:0021930
GO:0021940
GO:0023052
GO:0030163
GO:0030297
GO:0030335
GO:0030669
GO:0031093
GO:0031410
GO:0036211
GO:0038134
GO:0042327
GO:0043226
GO:0043388
GO:0043406
GO:0043410
GO:0045840
GO:0045893
GO:0046425
GO:0048018
GO:0048754
GO:0048856
GO:0048870
GO:0050673
GO:0050679
GO:0050730
GO:0050731
GO:0051048
GO:0051897
GO:0060749
GO:0070062
GO:0070371
GO:0090263
GO:0090279
GO:0090370
GO:0098772
GO:0140014
GO:1900127
GO:1901135
GO:1902966
GO:1905278
GO:2000008
GO:2000060
HMNXSV003008765
HMNXSV003036788
ILMN_1690733
PH_hs_0025117
TC04000568.hg
X04571_at
g6031163_3p_at
g6031163_3p_x_at
Participates
as a member of
EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Other forms of this molecule
Pro-EGF [extracellular region]
Pro-EGF [platelet alpha granule lumen]
EGF [extracellular region]
Pro-EGF [plasma membrane]
Inferred To
cue [clathrin-coated endocytic vesicle membrane]
(Drosophila melanogaster)
Egf [clathrin-coated endocytic vesicle membrane]
(Mus musculus)
Egf [clathrin-coated endocytic vesicle membrane]
(Rattus norvegicus)
Homologues of EGF [clathrin-coated endocytic vesicle membrane]
(Caenorhabditis elegans)
Homologues of EGF [clathrin-coated endocytic vesicle membrane]
(Drosophila melanogaster)
rme-2 [clathrin-coated endocytic vesicle membrane]
(Caenorhabditis elegans)
EGF [clathrin-coated endocytic vesicle membrane]
(Caenorhabditis elegans)
EGF [clathrin-coated endocytic vesicle membrane]
(Canis familiaris)
EGF [clathrin-coated endocytic vesicle membrane]
(Gallus gallus)
EGF [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
arr [clathrin-coated endocytic vesicle membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001171602.1
,
NP_001171601.1
,
NP_001954.2
OpenTargets
ENSG00000138798
HPA
ENSG00000138798-EGF
GeneCards
P01133
Ensembl
ENST00000503392
,
ENSP00000421384
,
ENSP00000265171
,
ENST00000509793
,
ENSG00000138798
,
ENST00000265171
,
ENSP00000424316
PRO
P01133
Pharos - Targets
P01133
Orphanet
18428
HMDB Protein
HMDBP02438
PDB
2KV4
,
1IVO
,
8HGS
,
7SZ0
,
7SYD
,
7SZ1
,
8HGO
,
7SYE
,
3NJP
,
1NQL
,
1P9J
,
7OM4
,
1JL9
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.973
29
UniProt:P10620 MGST1
3
MGST1 [azurophil granule membrane]
(R-HSA-6799226)
MGST1 [plasma membrane]
(R-HSA-6806259)
MGST1 [endoplasmic reticulum membrane]
(R-HSA-158545)
0.556
3
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