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About
What is Reactome ?
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Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
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FAQ
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EGF [extracellular region]
Stable Identifier
R-HSA-179863
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Epidermal Growth Factor
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
NFE2L2 regulating tumorigenic genes (Homo sapiens)
NFE2L2 dependent EGF expression (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Developmental Biology (Homo sapiens)
Developmental Cell Lineages (Homo sapiens)
Differentiation of keratinocytes in interfollicular epidermis in mammalian skin (Homo sapiens)
Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Transit-amplifying cell of basal layer differentiates into keratinocyte of spinosum layer in interfollicular epidermis (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by EGFR in Cancer (Homo sapiens)
Signaling by EGFRvIII in Cancer (Homo sapiens)
Constitutive Signaling by EGFRvIII (Homo sapiens)
EGFRvIII cancer variant does not bind EGF ligand (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by Ligand-Responsive EGFR Variants in Cancer (Homo sapiens)
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants (Homo sapiens)
Binding of CBL to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:CBL [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Binding of EGF to ligand-responsive EGFR mutants (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Binding of GRB2:SOS1 complex to phosphorylated ligand-responsive EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Binding of PI3K to complex of GRB2:GAB1 and ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Binding of SHC1 to p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:SHC1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors (Homo sapiens)
Resistant ligand-responsive EGFR mutants [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Resistant ligand-responsive EGFR mutants:Covalent EGFR TKIs [plasma membrane] (Homo sapiens)
Resistant ligand-responsive EGFR mutants [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Dissociation of phosphorylated PLCG1 from ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-induced dimerization of ligand-responsive EGFR mutants (Homo sapiens)
EGF:Ligand-responsive EGFR mutants dimer [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Inefficient ubiquitination of ligand-responsive p-6Y-EGFR mutants by p-Y371-CBL (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:CBL [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y371-CBL [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants (Homo sapiens)
Active dimers of ligand-responsive EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants dimer [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Resistant ligand-responsive EGFR mutants [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Sensitive ligand-responsive EGFR mutants:Non-covalent EGFR TKIs [plasma membrane] (Homo sapiens)
Active dimers of ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PLCG1 binds to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:PLCG1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated SHC1 in complex with ligand-responsive p-6Y-EGFR mutants recruits GRB2:SOS1 complex (Homo sapiens)
Ligand responsive p-6Y-EGFR mutants:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:CBL [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y371-CBL [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:PLCG1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:SHC1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants) (Homo sapiens)
Ligand responsive p-6Y-EGFR mutants:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutants:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers (Homo sapiens)
Active dimers of ligand-responsive EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants dimer [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane] (Homo sapiens)
Dimers of EGF:Ligand-responsive p-6Y-EGFR mutants [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by Overexpressed Wild-Type EGFR in Cancer (Homo sapiens)
Inhibition of Signaling by Overexpressed EGFR (Homo sapiens)
Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers (Homo sapiens)
EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
EGFR:EGF-like ligands [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
EGFR:EGF-like ligands [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by ERBB2 in Cancer (Homo sapiens)
Signaling by ERBB2 ECD mutants (Homo sapiens)
ERBB2 ECD mutants heterodimerize with EGFR (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 ECD mutants:EGF:EGFR [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
GRB2:SOS1 binds to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate (Homo sapiens)
ERBB2 ECD mutants:EGF:EGFR [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind GRB2:GAB1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind PLCG1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind SHC1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR recruit GRB2:SOS1 through SHC1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-Y349,Y350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-Y349,Y350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by ERBB2 KD Mutants (Homo sapiens)
ERBB2 KD mutants heterodimerize (Homo sapiens)
Heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-Activated (EGFR,ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 KD mutants trans-autophosphorylate (Homo sapiens)
Heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind GRB2:GAB1 (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind GRB2:SOS1 (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind PLCG1 (Homo sapiens)
p-6Y-ERBB2 KD mutants (PLCG1):EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants (PLCG1):EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
p-6Y-ERBB2 KD mutants (PLCG1):EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants (PLCG1):EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants bind SHC1 (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:SHC1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:SHC1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants recruit GRB2:SOS1 through SHC1 (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,(p-ERBB3,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 KD mutants:Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-ERBB3,(p-EGFR,p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD heterodimers trans-autophosphorylate (Homo sapiens)
ERBB2 TMD/JMD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 TMD/JMD mutants hetrodimerize (Homo sapiens)
ERBB2 TMD/JMD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2 TMD/JMD heterodimers bind SHC1 (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind GRB2:SOS1 (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1 (Homo sapiens)
p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants recruit GRB2:SOS1 through SHC1 (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4) [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Homo sapiens)
Activated SRC,LCK,EGFR,INSR [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR dimer [plasma membrane] (Homo sapiens)
EGF:Phospho-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH3 (Homo sapiens)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Homo sapiens)
EGFR phosphorylates NOTCH3 (Homo sapiens)
EGF:p-6Y-EGFR dimer [plasma membrane] (Homo sapiens)
EGF:Phospho-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR dimer:NICD3 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR dimer [plasma membrane] (Homo sapiens)
EGF:Phospho-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
NOTCH3 binds activated EGFR (Homo sapiens)
EGF:p-6Y-EGFR dimer [plasma membrane] (Homo sapiens)
EGF:Phospho-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR dimer:NICD3 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR dimer [plasma membrane] (Homo sapiens)
EGF:Phospho-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by Non-Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PTK6 (Homo sapiens)
ERBB2 Activates PTK6 Signaling (Homo sapiens)
Activated ERBB2 binds PTK6 (BRK) (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 promotes PTK6 autophosphorylation (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Homo sapiens)
E2-mediated FOS gene expression (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer:p-Y397 PTK2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PTK2 autophosphorylates downstream of EGFR (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer:p-Y397 PTK2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y EGFR:PTK2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PTK2 binds activated EGFR (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y EGFR:PTK2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by EGFR (Homo sapiens)
EGFR autophosphorylation (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
EGFR:EGF-like ligands [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR binds EGF ligand (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR:EGF-like ligands [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR dimerization (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
EGFR:EGF-like ligands [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR:EGF-like ligands [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR downregulation (Homo sapiens)
Assembly of EGFR complex in clathrin-coated vesicles (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Binding of CBL to EGFR (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
CBL binds and ubiquitinates phosphorylated Sprouty (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
CBL ubiquitinates Sprouty (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
CBL-mediated ubiquitination of CIN85 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR binds EPS15, EPN1, EPS15L1 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR non-clathrin mediated endocytosis (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR phosphorylates EPS15 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Localization of CBL:GRB2 to the membrane (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PTPN12 dephosphorylates EGFR at Y1172 (Y1148) (Homo sapiens)
EGF:p-6Y-EGFR dimer [plasma membrane] (Homo sapiens)
EGF:Phospho-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-EGFR dimer dephosphorylated at Y1172 (Y1148) [plasma membrane] (Homo sapiens)
EGF:p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PTPN3 dephosphorylates EPS15 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylation of CBL (EGFR:CBL) (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Sprouty sequesters CBL away from active EGFR (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ubiquitination of stimulated EGFR (CBL) (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR interacts with phospholipase C-gamma (Homo sapiens)
Active PLC-gamma1 dissociates from EGFR (Homo sapiens)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGFR activates PLC-gamma1 by phosphorylation (Homo sapiens)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phospholipase C-gamma1 binds to the activated EGF receptor (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
GAB1 signalosome (Homo sapiens)
Activation of SHP2 through the binding to phospho-Gab1 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Dephosphorylation of Gab1 by SHP2 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-Y627,659-GAB1:SHP2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Dephosphorylation of PAG by SHP2 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
GAB1 phosphorylation by EGFR kinase (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
GRB2:GAB1 binds to phosphorylated EGFR (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K binds to EGF:EGFR:GRB2:GAB1 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SHP2 dephosphorylates Tyr 992 on EGFR (Homo sapiens)
EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Phospho-EGFR (-Y1016) dimer [plasma membrane] (Homo sapiens)
EGF-like ligands:Phospho-EGFR (- Y992) [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Sustained activation of SRC kinase by SHP2 (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
GRB2 events in EGFR signaling (Homo sapiens)
GRB2:SOS1 complex binds to EGF:EGFR complex (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylation of EGFR by SRC kinase (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
EGFR:EGF-like ligands [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Pro-EGF is cleaved to form mature EGF (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SHC1 events in EGFR signaling (Homo sapiens)
GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SHC1 binds to the phosphorylated EGF receptor:ligand complex (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SHC1 phosphorylation by phosphorylated EGFR (Homo sapiens)
EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by ERBB2 (Homo sapiens)
Downregulation of ERBB2 signaling (Homo sapiens)
MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers:MATK [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Homo sapiens)
Heterodimers of p-ERBB2 dephosphorylated at Y1248 [plasma membrane] (Homo sapiens)
Phosphorylated p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR:p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR:p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PTPN18 binds ERBB2:EGFR heterodimers (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Homo sapiens)
Phosphorylated ERBB2(dephosphorylated at Y1196,Y1112 and Y1248):EGFR heterodimers:PTPN18 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2(dephosphorylated at Y1196,Y1112 and Y1248):EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-Y1023,Y1139,Y1221,Y1222-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-Y877,Y1023,Y1139,Y1221,Y1222-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 Activates PTK6 Signaling (Homo sapiens)
Activated ERBB2 binds PTK6 (BRK) (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 promotes PTK6 autophosphorylation (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 Regulates Cell Motility (Homo sapiens)
MEMO1 binds RHOA:GTP:DIAPH1 (Homo sapiens)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2 heterodimers bind MEMO1 (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Homo sapiens)
ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:EGFR:ERBB2 [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Ligand-Activated EGFR/ERBB3/ERBB4 [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
GRB2 events in ERBB2 signaling (Homo sapiens)
GRB2:SOS1 complex binds phosphorylated EGFR:ERBB2 heterodimer (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI3K events in ERBB2 signaling (Homo sapiens)
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PLCG1 events in ERBB2 signaling (Homo sapiens)
PLCG1 binds to p-ERBB2:p-EGFR (Homo sapiens)
EGF:p-EGFR:p-ERBB2:PLCG1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PLCG1 phosphorylation by p-EGFR:p-ERBB2 (Homo sapiens)
EGF:p-EGFR:p-ERBB2:PLCG1 [plasma membrane] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SHC1 events in ERBB2 signaling (Homo sapiens)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers (Homo sapiens)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 heterodimers (Homo sapiens)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SHC1 binds phosphorylated ERBB2 heterodimers (Homo sapiens)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SHC1 phosphorylation by ERBB2 heterodimers (Homo sapiens)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Homo sapiens)
p-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SRC family kinases phosphorylate ERBB2 (Homo sapiens)
ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:EGFR:ERBB2 [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:EGFR:p-Y877-ERBB2 [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)
ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:EGFR:ERBB2 [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-6Y-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Homo sapiens)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
EGF:EGFR:p-Y877-ERBB2 [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Signaling by ERBB4 (Homo sapiens)
ERBB4 forms heterodimers with EGFR (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ERBB4:EGFR heterodimer [plasma membrane] (Homo sapiens)
EGF:EGFR [plasma membrane] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
Epsin family proteins bind ubiquitinated cargo (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Clathrin recruits PIK3C2A (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Homo sapiens)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
EGF-like ligands [extracellular region] (Homo sapiens)
EGF [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01133 EGF
Gene Names
EGF
Chain
signal peptide:1-22, chain:23-1207, chain:971-1023
Reference Genes
BioGPS Gene:1950 EGF
COSMIC (genes):EGF EGF
CTD Gene:1950 EGF
dbSNP Gene:1950 EGF
ENSEMBL:ENSG00000138798 EGF
ENSEMBL_homo_sapiens_GENE:ENSG00000138798.13 EGF
HGNC:3229 EGF
KEGG Gene (Homo sapiens):1950 EGF
Monarch:1950 EGF
NCBI Gene:1950 EGF
OMIM:131530 EGF
UCSC:P01133 EGF
Reference Transcript
RefSeq:NM_001178130.2 EGF
RefSeq:NM_001963.5 EGF
RefSeq:NM_001178131.2 EGF
Other Identifiers
11727113_at
11751935_a_at
11756749_a_at
1542_at
16969729
1950
206254_PM_at
206254_at
2739313
2739314
2739315
2739316
2739324
2739325
2739326
2739327
2739328
2739335
2739336
2739338
2739339
2739340
2739341
2739342
2739343
2739344
2739346
2739347
2739348
2739350
2739353
2739354
2739357
2739358
2739359
2739360
2739364
2739365
2739367
2739368
2739369
2739370
2739371
2739372
2739373
53431_at
8096845
A_14_P108123
A_14_P113507
A_14_P120827
A_23_P155979
GE58272
GE894110
GO:0000278
GO:0001525
GO:0001938
GO:0002092
GO:0005085
GO:0005154
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005765
GO:0005773
GO:0005886
GO:0005975
GO:0006351
GO:0006355
GO:0007173
GO:0008083
GO:0008283
GO:0008284
GO:0010595
GO:0010628
GO:0010800
GO:0016020
GO:0016192
GO:0021930
GO:0021940
GO:0023052
GO:0030163
GO:0030297
GO:0030335
GO:0030669
GO:0031093
GO:0031410