Reactome | MGST1 [endoplasmic reticulum membrane]

MGST1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-158545

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Microsomal glutathione S-transferase 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P10620 MGST1

Gene Names

MGST1, GST12, MGST

Chain

chain:1-155

Reference Genes

BioGPS Gene:4257 MGST1

COSMIC (genes):MGST1 MGST1

CTD Gene:4257 MGST1

dbSNP Gene:4257 MGST1

ENSEMBL:ENSG00000008394 MGST1

HGNC:7061 MGST1

KEGG Gene (Homo sapiens):4257 MGST1

Monarch:4257 MGST1

NCBI Gene:4257 MGST1

OMIM:138330 MGST1

UCSC:P10620 MGST1

Reference Transcript

Other Identifiers

0000520519

0002470039

0003450093

0003710731

11724470_s_at

11724471_x_at

11747570_a_at

1565162_s_at

224918_x_at

231736_x_at

3406595

3406596

3406597

3406599

3406601

3406604

3406612

3406613

3406614

3406619

4257

7954196

A_23_P36658

GE80049

GO:0000003

GO:0002376

GO:0003674

GO:0004364

GO:0004602

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005739

GO:0005741

GO:0005764

GO:0005773

GO:0005777

GO:0005778

GO:0005783

GO:0005789

GO:0005886

GO:0006790

GO:0006810

GO:0006950

GO:0008150

GO:0009058

GO:0010243

GO:0016020

GO:0016021

GO:0016192

GO:0016491

GO:0016740

GO:0016765

GO:0019748

GO:0030154

GO:0031410

GO:0032496

GO:0033327

GO:0034635

GO:0035577

GO:0042493

GO:0042802

GO:0043167

GO:0043226

GO:0043231

GO:0043295

GO:0043312

GO:0045177

GO:0046222

GO:0048856

GO:0071449

GO:0098869

GO:1901687

HMNXSV003046714

HMNXSV003052859

Hs.790.2.S1_3p_s_at

Hs2.421244.1.S1_3p_s_at

ILMN_1687387

ILMN_1694849

ILMN_1781952

ILMN_1803033

ILMN_2355168

PH_hs_0033090

TC12002266.hg

U46499_at

Participates

as a component of

MGST1 trimer [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

MGST1 [azurophil granule membrane]

MGST1 [plasma membrane]

Inferred To

Mgstl [endoplasmic reticulum membrane] (Drosophila melanogaster)

MGST1 [endoplasmic reticulum membrane] (Canis familiaris)

MGST1 [endoplasmic reticulum membrane] (Gallus gallus)

mgst1.2 [endoplasmic reticulum membrane] (Danio rerio)

Mgst1 [endoplasmic reticulum membrane] (Mus musculus)

Mgst1 [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001247440.1, NP_665707.1, NP_064696.1, NP_001247441.1, NP_665735.1, NP_001254527.1, NP_665734.1

OpenTargets

ENSG00000008394

HPA

ENSG00000008394-MGST1

GeneCards

P10620

Ensembl

ENSP00000379512, ENST00000010404, ENSP00000010404, ENST00000396207, ENST00000396210, ENST00000535309, ENSP00000438308, ENSP00000379510, ENSG00000008394, ENSP00000379513, ENST00000396209

PRO

P10620

Pharos - Targets

P10620

GlyGen

P10620

HMDB Protein

HMDBP00818

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75084 FZD7	1	FZD7 [plasma membrane] (R-HSA-517394)	0.556	3
UniProt:P01133 EGF	5	Pro-EGF [extracellular region] (R-HSA-54209) Pro-EGF [plasma membrane] (R-HSA-179888) EGF [clathrin-coated endocytic vesicle membrane] (R-HSA-8869086) Pro-EGF [platelet alpha granule lumen] (R-HSA-139875) EGF [extracellular region] (R-HSA-179863)	0.556	3
UniProt:Q8WX92 NELFB	3	NELFB [nucleoplasm] (R-HSA-112427) NELFB [mitochondrial outer membrane] (R-HSA-9603553) NELFB [cytosol] (R-HSA-9603526)	0.524	2