Homodimers and possibly heterodimers of TFAP2A and TFAP2C, in complex with CITED2, stimulate transcription of the PITX2 gene, involved in left-right patterning and heart development (Bamforth et al. 2004, Li et al. 2012).
Anderson, RH, Bhattacharya, S, Farthing, CR, Broadbent, C, Neubauer, S, Bragança, J, Clarke, K, Bamforth, SD, Schneider, JE, Michell, AC, Norris, D, Brown, NA
Pan, H, Guan, L, Li, Q, Su, D, Ma, X
© 2022 Reactome