Binding of TFAP2A (AP-2 alpha) dimer to AP-2 response elements in the VEGFA gene promoter results in repression of VEGFA expression (Ruiz et al. 2004). CITED2, a transcription co-factor of TFAP2A, also represses VEGFA transcription, but the mechanism has not been established (Li et al. 2012).
Bar-Eli, M, Song, R, Ruiz, M, Pettaway, C, Stoeltzing, O, Ellis, L
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