TFAP2C translocates to the nucleus

Stable Identifier
R-HSA-8864577
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
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TFAP2C translocates to the nucleus
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Like other AP-2 (TFAP2) transcription factor family members, TFAP2C (AP-2 gamma) mainly localizes to the nucleus. WWOX inhibits nuclear translocation of TFAP2C (Aqeilan et al. 2004).
Literature References
PubMed ID Title Journal Year
15548692 Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor

Weigel, RJ, Palamarchuk, A, Herrero, JJ, Aqeilan, RI, Croce, CM, Pekarsky, Y

Cancer Res. 2004
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
TFAP2C:WWOX [cytosol] (Homo sapiens)
Active Unit
WWOX [cytosol]
Orthologous Events
TFAP2C translocates to the nucleus (Bos taurus)
TFAP2C translocates to the nucleus (Caenorhabditis elegans)
TFAP2C translocates to the nucleus (Canis familiaris)
TFAP2C translocates to the nucleus (Danio rerio)
TFAP2C translocates to the nucleus (Drosophila melanogaster)
TFAP2C translocates to the nucleus (Gallus gallus)
TFAP2C translocates to the nucleus (Mus musculus)
TFAP2C translocates to the nucleus (Rattus norvegicus)
TFAP2C translocates to the nucleus (Sus scrofa)
TFAP2C translocates to the nucleus (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2016-03-14)
Reviewed
Zarelli, VE  (2016-05-04)
Bogachek, MV  (2016-05-17)
Dawid, IB  (2016-05-04)
Weigel, RJ  (2016-05-17)
Created
Orlic-Milacic, M  (2016-03-16)
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