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Ub-K839-VLDLR [plasma membrane]
Stable Identifier
R-HSA-8855136
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Very low-density lipoprotein receptor, VLDLR_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein clearance (Homo sapiens)
VLDLR internalisation and degradation (Homo sapiens)
MYLIP dimer ubiquitinates VLDLR on Lys-839 (Homo sapiens)
Ub-K839-VLDLR [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P98155 VLDLR
Gene Names
VLDLR
Chain
signal peptide:1-27, chain:28-873
Reference Genes
BioGPS Gene:7436 VLDLR
COSMIC (genes):VLDLR VLDLR
CTD Gene:7436 VLDLR
dbSNP Gene:7436 VLDLR
ENSEMBL:ENSG00000147852 VLDLR
HGNC:12698 VLDLR
KEGG:hsa:7436 VLDLR
Monarch:7436 VLDLR
NCBI Gene:7436 VLDLR
OMIM:192977 VLDLR
UCSC:P98155 VLDLR
Reference Transcript
RefSeq:NM_001018056.2 VLDLR
RefSeq:NM_003383.4 VLDLR
Other Identifiers
11721181_a_at
17083197
209822_PM_s_at
209822_s_at
3160176
3160177
3160178
3160179
3160180
3160182
3160183
3160185
3160186
3160187
3160188
3160189
3160190
3160191
3160192
3160193
3160194
3160195
3160196
3160197
3160198
3160200
3160201
3160202
3160203
3160204
3160205
3160206
3160207
3160208
3160209
3160210
3160211
3160212
3160213
3160214
3160215
3160216
3160217
3160218
3160219
3160220
3160221
3160222
3160223
36873_at
69420_at
7436
8154100
A_23_P43476
A_32_P128586
A_33_P3284925
D16532_at
GE57664
GE60482
GE733538
GO:0005041
GO:0005509
GO:0005515
GO:0005615
GO:0005765
GO:0005886
GO:0005905
GO:0006629
GO:0006869
GO:0006897
GO:0006898
GO:0007165
GO:0007399
GO:0007613
GO:0008203
GO:0016020
GO:0016192
GO:0021517
GO:0030229
GO:0034185
GO:0034189
GO:0034361
GO:0034436
GO:0034447
GO:0038024
GO:0038025
GO:0038026
GO:0043235
GO:0045202
GO:0048306
GO:0048813
GO:0048856
GO:0050877
GO:0051963
GO:0060089
GO:0098978
GO:1900006
HMNXSV003023004
ILMN_1675092
ILMN_2361862
PH_hs_0024141
TC09000015.hg
g437386_3p_a_at
Participates
as an output of
MYLIP dimer ubiquitinates VLDLR on Lys-839 (Homo sapiens)
Other forms of this molecule
VLDLR [lysosomal membrane]
VLDLR [plasma membrane]
Inferred To
Vldlr [plasma membrane]
(Mus musculus)
Vldlr [plasma membrane]
(Rattus norvegicus)
Ub-K839-VLDLR [plasma membrane]
(Bos taurus)
VLDLR [plasma membrane]
(Canis familiaris)
VLDLR [plasma membrane]
(Gallus gallus)
VLDLR [plasma membrane]
(Sus scrofa)
gldi-2 [plasma membrane]
(Caenorhabditis elegans)
LpR1 [plasma membrane]
(Drosophila melanogaster)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [plasma membrane]) at 839
Coordinate
839
Modification
K63polyUb [plasma membrane]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
ENSEMBL
ENST00000382100
,
ENST00000681306
,
ENSP00000506072
,
ENSP00000371532
OpenTargets
ENSG00000147852
HPA
ENSG00000147852-VLDLR
PRO
P98155
Pharos - Targets
P98155
GlyGen
P98155
Orphanet
VLDLR
PDB
8IHP
,
8UFC
,
3DPR
,
8UFB
,
1V9U
,
6BYV
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q60841
1
RELN [extracellular region]
(R-MMU-8854469)
0.775
7
UniProt:P30533 AMRP
0.77
6
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