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FLT3LG dimer [extracellular region]
Stable Identifier
R-HSA-8854740
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
FLT3 signaling by CBL mutants (Homo sapiens)
CBL mutants don't ubiquitinate FLT3 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:CBL mutants [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y GAB2:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y GAB2:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
Active FLT3 binds PTPN11 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to GRAP2 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:GRAP2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to GRB10 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:GRB10 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 dimer binds GRB2 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 phosphorylates CDKN1B (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2 binds GAB2 (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2 binds SOS1 (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Homo sapiens)
Active FLT3:GRB2:p-Y GAB2:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 binds PIK3R1 (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 binds PTPN11 (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Homo sapiens)
active FLT3:p-Y GRB10:PI3K [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:p-Y GRB10:PIK3R1 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:p-Y-GRB10 binds PIK3R1 (Homo sapiens)
active FLT3:p-Y GRB10 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:p-Y GRB10:PIK3R1 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3 binds type I TKI (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3 phosphorylates GRB10 (Homo sapiens)
active FLT3:GRB10 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:p-Y GRB10 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3 signaling through SRC family kinases (Homo sapiens)
Active FLT3 binds FYN (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:FYN [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds HCK (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:HCK [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to LCK (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:LCK [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to SYK (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SYK [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer binds FLT3 (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer:FLT3 binds FLT3 (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer:FLT3 dimer [plasma membrane] (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer:FLT3 dimer autophosphorylates (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer:FLT3 dimer [plasma membrane] (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated (Homo sapiens)
Active FLT3:GRB2:GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Negative regulation of FLT3 (Homo sapiens)
Active FLT3 binds to ABL2 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:ABL2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to CBL (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:CBL [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SH2B3 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SLA [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SLA2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to CSK (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:CSK [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to SH2B3 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SH2B3 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to SLA (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SLA [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to SLA2 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SLA2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to SOCS2 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SOCS2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3 binds to SOCS6 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SOCS6 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3 phosphorylates CBL (Homo sapiens)
active FLT3:CBL [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:pY-CBL [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Internalization of ubiquitinated FLT3 (Homo sapiens)
Ub-pY FLT3:FLT3LG dimer [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
PTPRJ dephosphorylates active FLT3 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
p-Y768,Y969 FLT3 dimer:FLT3LG dimer [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Ubiquitination of FLT3 (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
FLT3 E3 ubiquitin ligases [plasma membrane] (Homo sapiens)
active FLT3:SOCS2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:SOCS6 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
active FLT3:pY-CBL [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Ub-pY FLT3:FLT3LG dimer [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Homo sapiens)
Active FLT3:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
STAT5 Activation (Homo sapiens)
Activator phosphorylates STAT5 (Homo sapiens)
Activators of STAT5:STAT5 [cytosol] (Homo sapiens)
Activators of STAT5 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Activators of STAT5:p-STAT5 [cytosol] (Homo sapiens)
Activators of STAT5 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Activators bind STAT5 (Homo sapiens)
Activators of STAT5 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Activators of STAT5:STAT5 [cytosol] (Homo sapiens)
Activators of STAT5 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
p-STAT5 dissociates from activator:STAT5 complex (Homo sapiens)
Activators of STAT5 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Activators of STAT5:p-STAT5 [cytosol] (Homo sapiens)
Activators of STAT5 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Active FLT3:PTPN11 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y GAB2:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y GAB2:PI3K [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
Active FLT3:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor signalling cascade (Homo sapiens)
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
PI3K-containing complexes [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)
IGF1R signaling cascade (Homo sapiens)
IRS-related events triggered by IGF1R (Homo sapiens)
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
PI3K-containing complexes [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Homo sapiens)
Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] (Homo sapiens)
Active FLT3: GRB2 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
FLT3LG dimer [extracellular region] (Homo sapiens)
Participants
components
x 2
FLT3LG [extracellular region]
(Homo sapiens)
Participates
as a component of
p-Y768,Y969 FLT3 dimer:FLT3LG dimer [plasma membrane] (Homo sapiens)
Ub-pY FLT3:FLT3LG dimer [plasma membrane] (Homo sapiens)
FLT3LG dimer:FLT3 [plasma membrane] (Homo sapiens)
Active FLT3 [plasma membrane] (Homo sapiens)
as an input of
FLT3LG dimer binds FLT3 (Homo sapiens)
Inferred To
FLT3LG dimer [extracellular region]
(Bos taurus)
FLT3LG dimer [extracellular region]
(Caenorhabditis elegans)
FLT3LG dimer [extracellular region]
(Canis familiaris)
FLT3LG dimer [extracellular region]
(Drosophila melanogaster)
FLT3LG dimer [extracellular region]
(Gallus gallus)
FLT3LG dimer [extracellular region]
(Mus musculus)
FLT3LG dimer [extracellular region]
(Rattus norvegicus)
FLT3LG dimer [extracellular region]
(Sus scrofa)
FLT3LG dimer [extracellular region]
(Xenopus tropicalis)
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