Formation of the SCF-FBXL7 complex

Stable Identifier
R-HSA-8854052
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Formation of the SCF-FBXL7 complex
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FBXL7 associates with SKP1, CUL1 and RBX1 to form the SCF E3 ubiquitin ligase complex (Coon et al. 2011).
Literature References
PubMed ID Title Journal Year
22306998 Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest

Glasser, JR, Chen, BB, Coon, TA, Mallampalli, RK

Cell Cycle 2012
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
SCF complex assembly (0010265)
Orthologous Events
Formation of the SCF-FBXL7 complex (Bos taurus)
Formation of the SCF-FBXL7 complex (Canis familiaris)
Formation of the SCF-FBXL7 complex (Danio rerio)
Formation of the SCF-FBXL7 complex (Drosophila melanogaster)
Formation of the SCF-FBXL7 complex (Gallus gallus)
Formation of the SCF-FBXL7 complex (Mus musculus)
Formation of the SCF-FBXL7 complex (Rattus norvegicus)
Formation of the SCF-FBXL7 complex (Saccharomyces cerevisiae)
Formation of the SCF-FBXL7 complex (Sus scrofa)
Authored
Orlic-Milacic, M  (2016-01-27)
Reviewed
Lindon, C  (2016-05-13)
Grant, R  (2016-05-13)
Created
Orlic-Milacic, M  (2016-01-27)
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