Reactome | ENTPD5 [extracellular region]

ENTPD5 [extracellular region]

Stable Identifier

R-HSA-8851371

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5, CD39L4, CD39 antigen-like 4, PCPH

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Cell recruitment (pro-inflammatory response) (Homo sapiens)
        
        Purinergic signaling in leishmaniasis infection (Homo sapiens)
        
        NTPDase5 hydrolyzes nucleoside diphosphates (Homo sapiens)
        
        NPTDase5:Ca2+,Mg2+ [extracellular region] (Homo sapiens)
        
        ENTPD5 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75356 ENTPD5

Gene Names

ENTPD5, CD39L4, PCPH

Chain

signal peptide:1-24, chain:25-428

Reference Genes

BioGPS Gene:957 ENTPD5

COSMIC (genes):ENTPD5 ENTPD5

CTD Gene:957 ENTPD5

dbSNP Gene:957 ENTPD5

ENSEMBL:ENSG00000187097 ENTPD5

HGNC:3367 ENTPD5

KEGG:hsa:957 ENTPD5

Monarch:957 ENTPD5

NCBI Gene:957 ENTPD5

OMIM:603162 ENTPD5

UCSC:O75356 ENTPD5

Reference Transcript

Other Identifiers

11727176_a_at

1554094_PM_at

1554094_at

16794606

205757_PM_at

205757_at

226594_PM_at

226594_at

3239060

3571666

3571668

3571669

3571670

3571671

3571672

3571673

3571674

3571675

3571676

3571677

3571678

3571679

3571682

3571683

3571684

3571685

3571686

3571688

3571689

3571690

3571691

3571693

3571695

3571697

3571698

3571699

3571700

3571701

3571702

3571703

3571706

3571707

3571710

3571711

3571712

3571713

3571714

40666_at

48904_at

7980080

957

A_23_P117580

A_24_P25452

GE79880

GO:0003824

GO:0004382

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005783

GO:0006011

GO:0006256

GO:0006457

GO:0006486

GO:0006487

GO:0009134

GO:0016020

GO:0016787

GO:0017111

GO:0036384

GO:0043226

GO:0043262

GO:0045134

GO:0051084

GO:0055086

GO:1901135

GO:1990003

HMNXSV003017233

HMNXSV003048170

Hs.285290.1.A1_3p_at

Hs2.80975.2.A1_3p_at

ILMN_1745849

PH_hs_0022470

PH_hs_0038369

TC14001302.hg

TC14002083.hg

g4557426_3p_at

p28676

Participates

as a component of

NPTDase5:Ca2+,Mg2+ [extracellular region] (Homo sapiens)

Inferred To

Entpd5 [extracellular region] (Mus musculus)

Entpd5 [extracellular region] (Rattus norvegicus)

GDA1 [extracellular region] (Saccharomyces cerevisiae)

ENTPD5 [extracellular region] (Bos taurus)

ENTPD5 [extracellular region] (Canis familiaris)

ENTPD5 [extracellular region] (Drosophila melanogaster)

ENTPD5 [extracellular region] (Gallus gallus)

ENTPD5 [extracellular region] (Plasmodium falciparum)

ENTPD5 [extracellular region] (Sus scrofa)

gdp1 [extracellular region] (Schizosaccharomyces pombe)

uda-1 [extracellular region] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENSG00000187097, ENSP00000335246, ENST00000334696

OpenTargets

ENSG00000187097

IntEnz

3.6.1.6

GeneCards

ENTPD5

HPA

ENSG00000187097-ENTPD5

PRO

O75356

Pharos - Targets

O75356

HMDB Protein

HMDBP00879

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P06276 BCHE	2	BCHE [plasma membrane] (R-HSA-3640835) BCHE [extracellular region] (R-HSA-434469)	0.527	2