Reactome | POLDIP3 [nucleoplasm]

POLDIP3 [nucleoplasm]

Stable Identifier

R-HSA-8850646

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Polymerase delta-interacting protein 3, PDIP3_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - RNA Polymerase II Transcription Termination (Homo sapiens)
    - Cleavage of mRNA at the 3'-end (Homo sapiens)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        POLDIP3 [nucleoplasm] (Homo sapiens)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        POLDIP3 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BY77 POLDIP3

Gene Names

POLDIP3, KIAA1649, PDIP46

Chain

initiator methionine:, chain:2-421

Reference Genes

BioGPS Gene:84271 POLDIP3

COSMIC (genes):POLDIP3 POLDIP3

CTD Gene:84271 POLDIP3

dbSNP Gene:84271 POLDIP3

ENSEMBL:ENSG00000100227 POLDIP3

HGNC:23782 POLDIP3

KEGG:hsa:84271 POLDIP3

Monarch:84271 POLDIP3

NCBI Gene:84271 POLDIP3

OMIM:611520 POLDIP3

UCSC:Q9BY77 POLDIP3

Reference Transcript

Other Identifiers

11717005_a_at

11717006_a_at

11717007_x_at

11721103_a_at

11721104_x_at

16935648

210583_3p_at

210583_PM_at

210583_at

210584_PM_s_at

210584_s_at

212100_PM_s_at

212100_s_at

215357_PM_s_at

215357_s_at

243411_PM_at

243411_at

33868_at

3962462

3962464

3962486

3962487

3962495

3962496

3962497

3962498

3962499

3962500

3962501

3962502

3962503

3962505

3962508

3962509

3962510

3962511

3962512

3962513

3962515

3962517

3962518

3962519

3962520

3962522

3962523

4002860

68633_s_at

79555_at

8076465

84271

A_23_P502269

A_33_P3340085

GE61586

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006417

GO:0006913

GO:0016607

GO:0016973

GO:0036464

GO:0043226

GO:0044877

GO:0045727

GO:0051028

HMNXSV003013296

Hs.143719.0.A1_3p_at

Hs.278314.1.A1_3p_a_at

Hs.278314.2.A1_3p_a_at

ILMN_1685845

ILMN_1688000

PH_hs_0026372

TC22000849.hg

g13359268_3p_s_at

Participates

as an input of

TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Homo sapiens)

as a component of

Other forms of this molecule

POLDIP3 [cytosol]

Inferred To

cg6961 [nucleoplasm] (Drosophila melanogaster)

Homologues of POLDIP3 [nucleoplasm] (Dictyostelium discoideum)

Homologues of POLDIP3 [nucleoplasm] (Drosophila melanogaster)

YRA1 [nucleoplasm] (Saccharomyces cerevisiae)

mlo3 [nucleoplasm] (Schizosaccharomyces pombe)

Dmel\CG18259 [nucleoplasm] (Drosophila melanogaster)

Poldip3 [nucleoplasm] (Mus musculus)

Poldip3 [nucleoplasm] (Rattus norvegicus)

POLDIP3 [nucleoplasm] (Bos taurus)

POLDIP3 [nucleoplasm] (Canis familiaris)

POLDIP3 [nucleoplasm] (Dictyostelium discoideum)

POLDIP3 [nucleoplasm] (Gallus gallus)

POLDIP3 [nucleoplasm] (Sus scrofa)

Ghost homologue of POLDIP3 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of POLDIP3 [nucleoplasm] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000348657, ENSG00000100227, ENSP00000252116, ENSP00000252115, ENST00000252115

OpenTargets

ENSG00000100227

GeneCards

POLDIP3

HPA

ENSG00000100227-POLDIP3

PRO

Q9BY77

Pharos - Targets

Q9BY77

GlyGen

Q9BY77

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.623	3
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.558	3
UniProt:Q8IWV7 UBR1	1	UBR1 [cytosol] (R-HSA-976040)	0.499	2