Cytosolic guanine deaminase (GDA) catalyzes the reaction of guanine and water to form xanthine and ammonia (Yuan et al. 1999). The active enzyme is a homodimer (Murphy et al. 2009).
Murphy, PM, Bolduc, JM, Stoddard, BL, Baker, D, Gallaher, JL
Snyder, FF, McKay, DJ, Bin, JC, Yuan, G
guanine deaminase activity of GDA dimer [cytosol]
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