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XDH dimer [cytosol]
Stable Identifier
R-HSA-74244
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Azathioprine ADME (Homo sapiens)
XDH oxidises 6MP to 6TU (Homo sapiens)
XDH dimer [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
XDH dehydrogenates hypoxanthine to form xanthine (Homo sapiens)
XDH dimer [cytosol] (Homo sapiens)
XDH dehydrogenates xanthine to form urate (Homo sapiens)
XDH dimer [cytosol] (Homo sapiens)
XDH oxidizes hypoxanthine to form xanthine (Homo sapiens)
XDH dimer [cytosol] (Homo sapiens)
XDH oxidizes xanthine to form urate (Homo sapiens)
XDH dimer [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
17301077
Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate
Yamaguchi, Y
,
Nishino, T
,
Matsumura, T
,
Ichida, K
,
Okamoto, K
J Biochem
2007
Participants
components
FAD [cytosol]
x 2
Iron Sulphur Cluster [cytosol]
MPT [cytosol]
x 2
XDH [cytosol]
(Homo sapiens)
Inferred To
XDH dimer [cytosol]
(Bos taurus)
XDH dimer [cytosol]
(Caenorhabditis elegans)
XDH dimer [cytosol]
(Canis familiaris)
XDH dimer [cytosol]
(Dictyostelium discoideum)
XDH dimer [cytosol]
(Drosophila melanogaster)
XDH dimer [cytosol]
(Gallus gallus)
XDH dimer [cytosol]
(Mus musculus)
XDH dimer [cytosol]
(Rattus norvegicus)
XDH dimer [cytosol]
(Sus scrofa)
XDH dimer [cytosol]
(Xenopus tropicalis)
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