Reactome | beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2

beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2

Stable Identifier

R-HSA-73591

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

Synonyms

conversion of 3-ureidopropionate to beta-alanine

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic 3-ureidopropionase catalyzes the reaction of 3-ureidopropionate and water to form beta-alanine, CO2, and NH3 (van Kuilenberg et al. 2004).

Literature References

PubMed ID	Title	Journal	Year
15385443	beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities van Lenthe, H, van Gennip, AH, Zoetekouw, L, Ribes, A, van Kuilenberg, AB, Beke, E, van Cruchten, A, Meinsma, R, Hoffmann, GF, Wevers, RA, Kulik, W, Busch, R, Mayatepek, E, Rutsch, F, Voit, T, Assmann, B, Abeling, NG, Lorente, I, Stroomer, AE	Hum Mol Genet	2004