Reactome | beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2

beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2

Stable Identifier

R-HSA-73591

Type

Reaction

Species

Homo sapiens

Compartment

cytosol

Synonyms

conversion of 3-ureidopropionate to beta-alanine

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beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2

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Cytosolic 3-ureidopropionase catalyzes the reaction of 3-ureidopropionate and water to form beta-alanine, CO2, and NH3 (van Kuilenberg et al. 2004).

Literature References

PubMed ID	Title	Journal	Year
15385443	beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities van Lenthe, H, van Gennip, AH, Zoetekouw, L, Ribes, A, van Kuilenberg, AB, Beke, E, van Cruchten, A, Meinsma, R, Hoffmann, GF, Wevers, RA, Kulik, W, Busch, R, Mayatepek, E, Rutsch, F, Voit, T, Assmann, B, Abeling, NG, Lorente, I, Stroomer, AE	Hum Mol Genet	2004