5,6-dihydrouracil + H2O => beta-ureidopropionate

Stable Identifier
R-HSA-73589
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
conversion of 5,6-dihydrouracil to 3-ureidopropionate
Locations in the PathwayBrowser
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Cytosolic dihydropyrimidinase tetramer catalyzes the reaction of 5,6-dihydrouracil and water to form 3-ureidopropionate (Hamajima et al. 1998).

Literature References
PubMed ID Title Journal Year
9718352 Dihydropyrimidinase deficiency: structural organization, chromosomal localization, and mutation analysis of the human dihydropyrimidinase gene

Matsuda, K, Vreken, P, Kouwaki, M, Kidouchi, K, van Gennip, A, Ohba, S, Togari, H, Nonaka, M, Hamajima, N, Tamaki, N, Endo, Y, Sasaki, M, Wada, Y, De Abreu, R, Sumi, S, van Kuilenburg, A, Imaeda, M, Rotteveel, J

Am J Hum Genet 1998
Participants
Participates
Catalyst Activity

dihydropyrimidinase activity of DPYS tetramer [cytosol]

Orthologous Events
Created
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