Reactome | 5,6-dihydrouracil + H2O => beta-ureidopropionate

5,6-dihydrouracil + H2O => beta-ureidopropionate

Stable Identifier

R-HSA-73589

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

Synonyms

conversion of 5,6-dihydrouracil to 3-ureidopropionate

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5,6-dihydrouracil + H2O => beta-ureidopropionate

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Cytosolic dihydropyrimidinase tetramer catalyzes the reaction of 5,6-dihydrouracil and water to form 3-ureidopropionate (Hamajima et al. 1998).

Literature References

PubMed ID	Title	Journal	Year
9718352	Dihydropyrimidinase deficiency: structural organization, chromosomal localization, and mutation analysis of the human dihydropyrimidinase gene Hamajima, N, Kouwaki, M, Vreken, P, Matsuda, K, Sumi, S, Imaeda, M, Ohba, S, Kidouchi, K, Nonaka, M, Sasaki, M, Tamaki, N, Endo, Y, De Abreu, R, Rotteveel, J, van Kuilenburg, A, van Gennip, A, Togari, H, Wada, Y	Am J Hum Genet	1998